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Mendoza to Santiago from $6: 5 ways by bus, train, flight or car

Compare Travel Options and Prices

from
Mendoza, Argentina
to
Santiago, Chile

How to Get from Mendoza to Santiago: Cheapest, Fastest and Best Way

1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.

$6 by busBest price
181.5 kmDistance
2h 53m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Mendoza to Santiago with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

Company
Andesmar
Bus
Average Duration
8h 
Estimated price
$6-50
Recommended
Company
various
Bus
Average Duration
8h 
Estimated price
$6-50
Cheapest
route map
Distance: 181.5 km
Duration: 2h 53m

See more options

Company
various
Bus
Average Duration
7h  59m
Estimated price
$7-47
Company
various
Drive
Average Duration
4h  40m
Estimated price
$40-65
Company
various
Plane
Average Duration
2h  53m
Estimated price
$136-451

Traveling From Mendoza to Santiago

Traveling from Mendoza to Santiago offers you a chance to experience the lush vineyards and relaxed atmosphere of Mendoza, contrasting with Santiago's vibrant urban culture and stunning Andean backdrop.

Best Neighbourhoods in Santiago

Santiago boasts diverse neighborhoods, each offering its own character and charm.

Bellavista
• Vibrant street art and lively nightlife.
• Home to Pablo Neruda’s colorful house museum.
Lastarria
• Charming streets filled with cafes and boutiques.
• Hosts cultural events and art fairs regularly.
Providencia
• Mix of modern buildings and green parks.
• Excellent dining options and local markets.

Best Times To Visit Santiago's Attractions

Timing your visits to Santiago's attractions can greatly enhance your experience.

Cerro San Cristóbal
Early mornings or late afternoons offer cooler weather and fewer visitors.
La Moneda Palace
Weekday mornings provide a quieter atmosphere to appreciate the architecture.
Mercado Central
Visiting during lunchtime allows you to enjoy fresh seafood without the rush.

Santiago Weather: What to Expect Year-Round

Santiago enjoys a Mediterranean climate with warm, dry summers and mild, wet winters, making it a year-round destination. The best times to visit are from September to November and March to May, when the weather is pleasant and ideal for outdoor exploration.

Dining Recommendation in Santiago

Try the renowned "Pastel de Choclo" at Restaurante Galindo, which features a comforting corn pie that reflects Chilean flavors distinct from Mendoza's wine-centric cuisine. The lively atmosphere and emphasis on fresh, local ingredients provide a dining experience that captures Santiago's vibrant culinary essence.

Mendoza - Santiago operators

Explore transport companies operating between Mendoza and Santiago, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Bus Show bus routes
Contact phone
0810 122 1122
Website
https://www.andesmar.com/en/

Bus from Terminal Mendoza to Santiago de Chile

Average Duration
8h
Estimated price
$6-45
Contact phone
0800-122-2282
Website
http://catainternacional.com

Bus from Terminal Mendoza to Santiago

Average Duration
8h
Estimated price
$8-50
Contact phone
600 360 0224
Website
http://busesahumada.cl

Bus from Terminal Mendoza to Santiago de Chile - Los Héroes

Average Duration
6h
Estimated price
$4-45
Contact phone
0810 122 1122
Website
https://www.andesmar.com/en/

Bus from Terminal Mendoza to Terminal Sur de Santiago

Average Duration
6h 45m
Estimated price
$41-41
Contact phone
+54 9 261 662-2223
Website
http://mathostour.cl

Bus from Mendoza to Santiago

Average Duration
7h 30m
Estimated price
$41-41
Contact phone
+56 22 822 7500
Website
http://new.turbus.cl

Bus from Terminal Mendoza to Terminal Alameda - Turbus

Average Duration
8h
Estimated price
$6-45
Contact phone
+56 22 822 7509
Website
http://taschoapa.cl

Bus from Terminal Mendoza to Terminal Alameda - Turbus

Average Duration
7h
Estimated price
$46-46
Plane Show flights
Website
https://jetsmart.com

Plane from Mendoza (MDZ) to Santiago (SCL)

Average Duration
1h
Estimated price
$60-260
Website
https://latam.com

Plane from Mendoza (MDZ) to Santiago (SCL)

Average Duration
1h
Estimated price
$70-850
Website
https://aerolineas.com.ar

Plane from Mendoza (MDZ) to Santiago (SCL)

Average Duration
1h
Estimated price
$95-650
Website
https://skyairline.com

Plane from Mendoza (MDZ) to Santiago (SCL)

Average Duration
1h 1m
Estimated price
$55-400

Mendoza to Santiago: Overview of Bus, Train, Flight, and Car Trips

Traveling between Mendoza and Santiago offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.

🚗 Embark on a scenic journey from Mendoza to Santiago covering a distance of 355.7 km. Enjoy the breathtaking landscapes of the Andes mountains as you drive for approximately 4 hours and 40 minutes. 💸 Experience the freedom of the open road with prices ranging from $40 to $65 to make the journey from Mendoza to Santiago by car.
Average price
$40 - $65
🚆 Embark on a scenic train journey from Mendoza to Santiago. The route covers a distance of 185-187 km and takes around 7-8 hours to reach the vibrant Santiago Metropolitan Region. 🌄 Enjoy the picturesque landscapes as you travel through the spectacular Andes Mountains. 🚃 The bus from Terminal Mendoza to Santiago is a convenient option for travel between the two cities, taking approximately 7 hours to complete the journey.
🛫 The quickest way to travel from Mendoza to Santiago is by taking a direct flight, which typically lasts around 56 minutes. 💸 The prices for flights between Santiago and Mendoza can range from $136 to $451, providing options for different budget preferences. Overall, the journey by plane takes approximately 2 hours and 53 minutes.
Departure Point
Mendoza Airport
Arrival Point
Santiago Airport
🚌 The journey from Mendoza to Santiago by bus takes approximately 8 hours. 🌄 Enjoy the scenic route as you travel 186-189 km from Mendoza to Santiago. The Andesmar bus service offers a comfortable ride, with multiple departures and arrivals at Santiago de Chile station. 🎟️ Prices for the bus ticket can range from $6 to $50, offering an affordable and convenient way to travel between these two beautiful South American cities.
Departure Point
Terminal Mendoza station
Arrival Point
Santiago de Chile station
Useful tips for bus travellers
• Book your ticket in advance through Andesmar or other operators like Chilebus to secure your seat, especially during peak travel times or holidays—check schedules and purchase here: recorrido.cl
• Prepare for border crossing: make sure you have your passport ready, and be aware that the bus will make a stop for customs inspection, which may take some time; keep snacks and entertainment handy since the journey is around 8 hours.
• Upon arrival at Santiago's Terminal de Buses Sur, familiarize yourself with the station layout by using the map available at their official website (terminalesur.cl), and consider using the Metro for easy transport into the city—Line 6 is a direct link from the station.

Frequently asked questions

Find out more about the route from Mendoza to Santiago.

Or choose the category:
The distance between Mendoza and Santiago is 181.9 km. The road distance is 355.0 km. Traveling by plane is the quickest option, taking 2 hours and 53 minutes. If you choose to drive, it will take approximately 4 hours and 40 minutes, while a bus journey between the two cities typically takes around 8 hours.
The most cost-effective option for traveling from Mendoza to Santiago is by bus, with tickets ranging from $6 to $50. However, this mode of transport takes 8 hours to reach the destination. If you are looking for a quicker option, flying from Mendoza to Santiago is the most time-efficient choice, taking only 2 hours and 53 minutes, with ticket prices ranging from $130 to $460.
The prices of a bus ticket between Santiago and Mendoza can range from $6 to $50, depending on the type of service and amenities provided.
To travel from Mendoza to Santiago without using public transportation, you can opt to drive the 355.7 km distance. It takes around 4 hours and 40 minutes to reach Santiago from Mendoza by car. The cost of this journey by car typically varies between $40 to $65, providing you with the flexibility of exploring the scenic route at your own pace.
The best way to travel from Mendoza to Santiago without a car is by bus, which takes approximately 8 hours. There are various bus companies offering direct routes between the two cities, with ticket prices ranging from $6 to $50 depending on the class and amenities. The bus journey offers a comfortable and cost-effective way to pass through the beautiful Andes mountains and enjoy the scenic views along the way.
Yes, there is a direct link between Mendoza and Santiago via a bus service operated by Andesmar. The bus departs from Terminal Mendoza every three hours and the journey takes approximately 8 hours to reach Santiago de Chile.
The quickest direct flight from Mendoza Airport to Santiago Airport takes approximately 56 minutes. The prices for flights between Santiago and Mendoza can vary, typically ranging from $136 to $451 depending on factors such as the airline and time of booking.
In Santiago you have a wide range of accommodation options to choose from, with over 1,797 hotels available in the area. Prices for hotels in Santiago typically start at $59 per night, offering a variety of budget-friendly and luxury choices to suit different preferences and budgets.