Buses from Irvine to San Diego
🚌 The journey from Irvine to San Diego by bus involves transferring at Santa Ana Bus Stop. The total travel time, including transfers, is approximately 3 hours and 21 minutes. 🚆 Route 1 offers a quicker alternative, taking 1 hour and 55 minutes to cover the 82.4-mile distance between the two cities. Step 1 involves taking the Pacific Surfliner train operated by Amtrak, departing from Irvine and arriving in San Diego.