Buses from Santa Ana to Irvine
🌆 The bus departs from Main-1St station in Santa Ana and arrives at Main-Harvard station in Irvine. This direct route ensures a smooth and seamless commute between the two cities. 🕒 On average, the bus journey from Santa Ana to Irvine takes approximately 28 minutes. Sit back, relax, and enjoy the ride as you travel between these bustling Southern California cities.