
Mesa, AZ, USA to San Diego, CA, USA from $41: 4 ways by bus, train, flight or car
Compare Travel Options and Prices
How to Get from Mesa to San Diego: Cheapest, Fastest and Best Way
1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.
Compare Train, Bus, Flight, and Driving Options
Get detailed, step-by-step directions below for your trip from Mesa to San Diego with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

See more options
Traveling From Mesa to San Diego
The journey from Mesa to San Diego offers a striking contrast between Mesa's arid desert landscape and San Diego's vibrant coastal charm.
Best Neighbourhoods in San Diego
San Diego boasts diverse neighborhoods, each offering its own charm and attractions.
Best Times To Visit San Diego's Attractions
Maximize your enjoyment of San Diego's attractions with these timing tips.
San Diego Weather: What to Expect Year-Round
San Diego boasts a mild, Mediterranean climate with warm summers and cool winters, making it an appealing destination any time of year. Visiting in spring or fall typically offers pleasant temperatures and fewer crowds, enhancing your overall travel experience.
Dining Recommendation
In San Diego, try the fish tacos at Fisherman’s Wharf, a dish that captures the essence of the coastal cuisine with fresh seafood and zesty flavors. Unlike the Southwestern fare often found in Mesa, this vibrant coastal dining experience showcases local ingredients and a laid-back atmosphere, inviting you to savor the city’s unique culinary scene.
Mesa - San Diego operators
Explore transport companies operating between Mesa and San Diego, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Train from Center/Main St to 44th St/Washington
Bus from Phoenix Sky Harbor Airport/44th Street Station to Calexico Bus Station
Bus from Tempe to Riverside
Bus from Riverside to San Diego
Bus from Mexicali to Tijuana
Plane from Phoenix (PHX) to San Diego (SAN)
Plane from Phoenix (PHX) to San Diego (SAN)
Plane from Phoenix (PHX) to San Diego (SAN)
Mesa to San Diego: Overview of Bus, Train, Flight, and Car Trips
Traveling between Mesa and San Diego offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.
Frequently asked questions
Find out more about the route from Mesa to San Diego.
Trips from Mesa
- Mesa to Payson
- Mesa to Sedona
- Mesa to Nogales
- Mesa to Flagstaff
- Mesa to Prescott
- Mesa to Scottsdale
- Mesa to Show Low
- Mesa to Chandler
- Mesa to Queen Creek
- Mesa to Lake Havasu City
- Mesa to Los Angeles
- Mesa to Glendale
- Mesa to Yuma
- Mesa to Prescott Valley
- Mesa to Gilbert
- Mesa to Tucson
- Mesa to Tombstone
- Mesa to Phoenix
- Mesa to Gold Canyon
- Mesa to Tempe
- Mesa to Peoria
- Mesa to Provo
- Mesa to Pueblo
- Mesa to Amarillo
- Mesa to Gallup
- Mesa to Las Vegas
- Mesa to El Paso
- Mesa to Globe
- Mesa to St. George
- Mesa to Denver
- Mesa to Wickenburg
- Mesa to Page
- Mesa to Sioux Falls
- Mesa to Jerome
- Mesa to Grand Canyon
- Mesa to Sierra Vista
- Mesa to Surprise
- Mesa to Albuquerque
- Mesa to Ajo
- Mesa to Rockford
Trips to Payson
- Santa Monica to San Diego
- Los Angeles to San Diego
- Santa Barbara to San Diego
- Newport Beach to San Diego
- Irvine to San Diego
- Pasadena to San Diego
- Anaheim to San Diego
- Mexico City to San Diego
- San Francisco to San Diego
- San Jose to San Diego
- Las Vegas to San Diego
- Fullerton to San Diego
- San Bernardino to San Diego
- Burbank to San Diego
- Phoenix to San Diego
- Riverside to San Diego
- Huntington Beach to San Diego
- Oxnard to San Diego
- Atlanta to San Diego
- Carlsbad to San Diego
- New York City to San Diego
- Salt Lake City to San Diego
- Minneapolis to San Diego
- Detroit to San Diego
- Laguna Beach to San Diego
- Norfolk to San Diego
- Miami to San Diego
- Calgary to San Diego
- Pittsburgh to San Diego
- Tampa to San Diego
- Escondido to San Diego
- Oceanside to San Diego
- Temecula to San Diego
- San Clemente to San Diego
- Saint Louis to San Diego
- Bakersfield to San Diego
- Santa Ana to San Diego
- Encinitas to San Diego
- Yuma to San Diego
- El Cajon to San Diego