San Francisco, CA, USA to Seneca, SC, USA from $50: 3 ways by bus, train, flight or car

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Get detailed, step-by-step directions below for your trip from San Francisco to Seneca with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

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2h  30m

Estimated price

$71-71

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Average Duration

3h  15m

Estimated price

$50-60

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Distance: 180 km

Duration: 2h 30m

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Average Duration

2h  45m

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$80-100

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Traveling From San Francisco to Seneca

Your journey from the vibrant, bustling streets of San Francisco to the serene, picturesque landscapes of Seneca offers a fascinating contrast between urban life and tranquil nature.

Best Neighbourhoods in Seneca

Seneca is home to diverse neighborhoods, each offering unique experiences.

Downtown Seneca

• Vibrant dining options and local shops.

• Hosts seasonal festivals and events.

Lake Hartwell

• Stunning waterfront views and outdoor activities.

• Great for fishing and water sports.

Clemson Boulevard

• Popular for family-friendly attractions.

• Easy access to major highways and amenities.

Best Times To Visit Seneca's Attractions

Timing your visit can enhance your experience at Seneca's highlights.

Lake Hartwell

Visit during weekdays in early morning for peaceful scenery and fewer crowds.

Oconee Station State Historic Site

Spring and fall are ideal for mild weather and fewer tourists.

Lush greenery at Seneca's parks

Early mornings on weekends offer quieter paths and fresh air.

Seneca Weather: What to Expect Year-Round

Seneca typically experiences a humid subtropical climate with hot summers and mild winters, making spring and fall the most pleasant times to visit. Weather can significantly influence your travel plans, so preparing for seasonal variations enhances your overall experience.

Dining Recommendation in Seneca

Try the fried catfish at the local favorite, The Glassy Mountain Restaurant, where the atmosphere is warm and inviting, showcasing genuine Southern hospitality. This dish contrasts sharply with San Francisco's seafood focus, offering a rich, comforting flavor profile that's deeply rooted in local ingredients.