
Santa Cruz, CA, USA to San Luis Obispo, CA, USA from $9: 7 ways by bus, train, flight or car
Compare Travel Options and Prices
How to Get from Santa Cruz to San Luis Obispo: Cheapest, Fastest and Best Way
1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.
Compare Train, Bus, Flight, and Driving Options
Get detailed, step-by-step directions below for your trip from Santa Cruz to San Luis Obispo with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

See more options
Traveling From Santa Cruz to San Luis Obispo
Traveling from Santa Cruz to San Luis Obispo offers a dynamic shift from the coastal vibrancy of Santa Cruz to the charming, laid-back ambiance of San Luis Obispo, where rolling hills and wine country await.
Best Neighborhoods in San Luis Obispo
San Luis Obispo boasts diverse neighborhoods, each showcasing its own charm and attractions.
Best Times To Visit San Luis Obispo's Attractions
Timing your visit can elevate your San Luis Obispo experience significantly.
San Luis Obispo Weather: What to Expect Year-Round
San Luis Obispo boasts a Mediterranean climate with mild, wet winters and sunny, dry summers, making spring and fall ideal for outdoor activities. The weather plays a significant role in your travel plans, as pleasant temperatures enhance visits to parks, vineyards, and local events.
Dining Recommendation in San Luis Obispo
Try the tri-tip sandwich at Firestone Grill, where the smoky, grilled flavor brings a hearty twist that contrasts with the fresh seafood focus often found in Santa Cruz. The vibrant atmosphere and use of locally sourced ingredients deliver a dining experience that reflects the culinary identity of the Central Coast.
Santa Cruz - San Luis Obispo operators
Explore transport companies operating between Santa Cruz and San Luis Obispo, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Bus from Front & Soquel Ave to Watsonville Transit Center
Bus from Soquel Ave & Front to Diridon Station
Bus from Ocean & Water to Diridon Station
Bus from Salinas Train Station to San Luis Obispo Railroad Museum
Train from Salinas to San Luis Obispo
Train from San Jose to San Luis Obispo
Train from San Jose Diridon to Millbrae
Plane from San Francisco Airport to San Luis Obispo County Apt Airport
Santa Cruz to San Luis Obispo: Overview of Bus, Train, Flight, and Car Trips
Traveling between Santa Cruz and San Luis Obispo offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.
Frequently asked questions
Find out more about the route from Santa Cruz to San Luis Obispo.
Trips from Santa Cruz
- Santa Cruz to Los Gatos
- Santa Cruz to Davis
- Santa Cruz to San Francisco
- Santa Cruz to Palo Alto
- Santa Cruz to Walnut Creek
- Santa Cruz to San Jose
- Santa Cruz to Santa Monica
- Santa Cruz to Carmel-by-the-Sea
- Santa Cruz to Salinas
- Santa Cruz to Sacramento
- Santa Cruz to Big Sur
- Santa Cruz to Santa Rosa
- Santa Cruz to Berkeley
- Santa Cruz to Monterey
- Santa Cruz to Aptos
- Santa Cruz to Los Angeles
- Santa Cruz to Santa Barbara
- Santa Cruz to Fresno
- Santa Cruz to Ventura
- Santa Cruz to Half Moon Bay
- Santa Cruz to Bakersfield
- Santa Cruz to Roseville
- Santa Cruz to Watsonville
- Santa Cruz to Reno
- Santa Cruz to Moss Landing
- Santa Cruz to Gilroy
- Santa Cruz to Capitola
- Santa Cruz to Santa Maria (Santa Barbara County)
- Santa Cruz to Sequoia National Park
- Santa Cruz to Oakland
- Santa Cruz to San Diego
- Santa Cruz to Modesto
- Santa Cruz to Elk Grove
- Santa Cruz to Merced
- Santa Cruz to Livermore
- Santa Cruz to King City
- Santa Cruz to Mammoth Lakes
- Santa Cruz to Dallas
- Santa Cruz to New York City
- Santa Cruz to Hayward
Trips to Los Gatos
- Santa Barbara to San Luis Obispo
- Santa Rosa to San Luis Obispo
- San Jose to San Luis Obispo
- Thousand Oaks to San Luis Obispo
- Los Angeles to San Luis Obispo
- Salinas to San Luis Obispo
- Irvine to San Luis Obispo
- San Diego to San Luis Obispo
- Fresno to San Luis Obispo
- San Francisco to San Luis Obispo
- Long Beach to San Luis Obispo
- Santa Clarita to San Luis Obispo
- Sacramento to San Luis Obispo
- Bakersfield to San Luis Obispo
- Ventura to San Luis Obispo
- Morro Bay to San Luis Obispo
- Palm Springs to San Luis Obispo
- Monterey to San Luis Obispo
- Burbank to San Luis Obispo
- Portland to San Luis Obispo
- Tucson to San Luis Obispo
- Hayward to San Luis Obispo
- Seattle to San Luis Obispo
- Reno to San Luis Obispo
- Chicago to San Luis Obispo
- Paso Robles to San Luis Obispo
- Pismo Beach to San Luis Obispo
- Santa Maria (Santa Barbara County) to San Luis Obispo
- Solvang to San Luis Obispo
- Oakland to San Luis Obispo
- Nipomo to San Luis Obispo
- Arroyo Grande to San Luis Obispo
- Phoenix to San Luis Obispo
- Boise to San Luis Obispo
- Eugene to San Luis Obispo
- Dallas to San Luis Obispo
- Nashville to San Luis Obispo
- Las Vegas to San Luis Obispo
- King City to San Luis Obispo
- Denver to San Luis Obispo