Key West, FL, USA to Panama City, FL, USA from $84: 7 ways by bus, train, flight or car

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How to Get from Key West to Panama City: Cheapest, Fastest and Best Way

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$84 - PlaneBest price

735 kmDistance

5h 20m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Key West to Panama City with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

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Traveling From Key West to Panama City

Journeying from the laid-back tropical vibe of Key West to the vibrant, bustling atmosphere of Panama City offers you a contrast that showcases Florida's diverse lifestyles.

Best Neighbourhoods in Panama City

Panama City offers diverse neighborhoods, each with its own charm and atmosphere.

St. Andrews

• Quaint historic homes and scenic waterfront views.

• Great dining options and local breweries.

Panama City Beach

• Stunning white sand beaches and crystal-clear waters.

• Vibrant nightlife and numerous water sports activities.

Downtown Panama City

• Mix of modern convenience and historical landmarks.

• Access to shops, restaurants, and cultural attractions.

Best Times To Visit Panama City's Attractions

Timing your visits to attractions in Panama City can enhance your experience and help you avoid crowds.

Panama City Beach

Early mornings and weekdays are best for a peaceful beach experience.

St. Andrews State Park

Visit during weekdays in spring for fewer visitors and beautiful blooms.

Downtown Panama City

Late afternoons on weekdays offer a less crowded shopping and dining experience.

Panama City Weather: What to Expect Year-Round

Panama City enjoys a humid subtropical climate with warm summers and mild winters, making it an appealing destination year-round. The best times to visit are spring and fall when temperatures are comfortable, and you’ll find outdoor activities more enjoyable without the intense heat.

Dining Recommendation

Try the Southern-style fried catfish at The Capt. Anderson's Restaurant for a hearty contrast to the seafood-centric dishes of Key West. This local gem showcases fresh ingredients and a warm, welcoming atmosphere that reflects Panama City's rich culinary heritage.

Key West - Panama City operators

Explore transport companies operating between Key West and Panama City, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Plane Show flights

Website

aa.com

Plane from Key West (EYW) to Panama City (ECP)

Average Duration

5h 20m

Estimated price

$1322-1325

Plane from Key West (EYW) to Tallahassee (TLH)

Average Duration

4h 22m

Estimated price

$1322-4592

Plane from Key West (EYW) to Valparaiso (VPS)

Average Duration

5h 26m

Estimated price

$1329-13240

Plane from Key West (EYW) to Pensacola (PNS)

Average Duration

4h 14m

Estimated price

$1322-1327

Website

delta.com

Plane from Key West (EYW) to Panama City (ECP)

Average Duration

5h 13m

Estimated price

$1324-4593

Plane from Key West (EYW) to Tallahassee (TLH)

Average Duration

4h 51m

Estimated price

$4594-4593

Plane from Key West (EYW) to Valparaiso (VPS)

Average Duration

5h 19m

Estimated price

$1324-4593

Plane from Key West (EYW) to Pensacola (PNS)

Average Duration

5h 32m

Estimated price

$1324-4595

Website

silverairways.com

Plane from Key West (EYW) to Tallahassee (TLH)

Average Duration

8h 30m

Estimated price

$1322-1327

Plane from Key West (EYW) to Pensacola (PNS)

Average Duration

5h 15m

Estimated price

$1322-13240

Bus

Contact phone

+1 (855) 626-8585

Website

flixbus.com

Bus from Key West to Miami Airport Station

Average Duration

3h 55m

Estimated price

$841-1324

Contact phone

+1 877 733 0724

Website

redcoachusa.com

Bus from Orlando RedCoach Station to Tallahassee Downtown

Average Duration

4h 45m

Estimated price

$842-843

Contact phone

+1 214-849-8100

Website

greyhound.com

Bus from Miami Airport Station to Tallahassee Bus Station

Average Duration

12h 50m

Estimated price

$4594-840

Train

Contact phone

+1 831-539-2901

Website

gobrightline.com

Train from Miami to Orlando

Average Duration

Estimated price

$4597-840

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Other from Waffle House - Marianna, FL to Panama City

Average Duration

1h 7m

Estimated price

$1322-4100

Key West to Panama City: Overview of Bus, Train, Flight, and Car Trips

Traveling between Key West and Panama City offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.

🚗 Embark on a scenic road trip from Key West to Panama City, covering a distance of 744 miles. Delight in the journey through the picturesque Florida landscape, with an estimated driving time of 13 hours and 8 minutes. 💰 Budget-savvy travelers will appreciate the diverse price range to reach Panama City from Key West by car, ranging from $130 to $200. Make sure to plan ahead and choose the option that best fits your travel budget while enjoying the flexibility of a road trip.

Average price

$130 - $200

🛫 The trip from Key West to Panama City by plane involves a stopover, with the quickest flight lasting 4 hours and 41 minutes. 💰 Prices for flights between the two cities can vary, ranging from $132 to $459, with a total travel time of approximately 5 hours and 20 minutes.

Departure Point

Key West Airport

Arrival Point

Panama City Airport. The quickest flight takes 4h 41m and has one stopover

Useful tips for plane travellers

• When booking your flight from Key West to Panama City, consider choosing American Airlines or Delta for the most convenient one-stop options, as these airlines have frequent connections via major hubs like Miami or Atlanta which can help minimize layover time.

• Upon arriving at Northwest Florida Beaches International Airport (ECP) in Panama City, be prepared for a relatively small airport layout with limited signage; it's advisable to download the airport map ahead of time to efficiently locate amenities and navigate to your next destination.

• Taxi fares from ECP to downtown Panama City typically range from $30 to $45, so make sure to verify the approximate cost before leaving the airport and consider using rideshare options for potentially more affordable rates; check local transportation schedules on ECP's website for the latest updates.

Frequently asked questions

Find out more about the route from Key West to Panama City.

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The distance between Key West and Panama City is approximately 457 miles. By plane, it typically takes around 5 hours and 39 minutes to travel between the two cities. Alternatively, if you choose to drive, the road distance is about 744 miles, and it usually takes around 13 hours and 8 minutes to drive from Panama City to Key West. Another option is to fly to Pensacola from Key West, which takes around 7 hours and 44 minutes, and then drive to Panama City.

The most cost-effective option for traveling from Key West to Panama City is to drive, with costs ranging from $130 to $200. However, this option also takes the longest time, with a travel duration of approximately 13 hours and 8 minutes. If time-efficiency is a priority, the quickest option would be to fly, which takes approximately 5 hours and 39 minutes and costs between $380 and $1100. Overall, the choice between cost-effectiveness and time-efficiency depends on individual preferences and priorities.

To get from Key West to Panama City without using public transportation, the most convenient option is to drive. The distance between the two cities is approximately 744 miles, and it takes around 13 hours and 8 minutes to complete the journey by car. The prices for renting a car and fuel costs can vary, typically ranging from $130 to $200.

To travel from Key West to Panama City without a car, the best option is to take a combination of bus, train, and taxi. The journey takes approximately 18 hours and 51 minutes and the cost ranges from $280 to $600. Start by taking a bus or taxi to the nearest train station, then board a train to reach a station closer to Panama City. From there, take a taxi to reach your final destination. This route is convenient for those who prefer not to drive and offers an opportunity to relax and enjoy the scenery along the way.

The flight between Key West and Panama City typically takes around 3 hours and 59 minutes with one stopover. However, there is no direct flight between the two cities. The cost of a flight between Panama City and Key West can range from $381 to $1029, depending on factors such as airline, time of booking, and availability. It is recommended to compare prices and book in advance to secure the best deals on flights.

There is a wide range of accommodation options available near Panama City. With over 1321 hotels to choose from, visitors can find options to suit various budgets and preferences. Prices for hotels in the area start at $69 per night, providing affordable options for travelers. It is recommended to book in advance to ensure availability and secure the best rates.

Key West, FL, USA to Panama City, FL, USA from $84: 7 ways by bus, train, flight or car

How to Get from Key West to Panama City: Cheapest, Fastest and Best Way

Compare Train, Bus, Flight, and Driving Options

See more options

Traveling From Key West to Panama City

Best Neighbourhoods in Panama City

Best Times To Visit Panama City's Attractions

Panama City Weather: What to Expect Year-Round

Dining Recommendation

Key West - Panama City operators

Key West to Panama City: Overview of Bus, Train, Flight, and Car Trips

Useful tips for plane travellers

Frequently asked questions

Trips from Key West

Trips to Panama City

Popular routes