
Mattoon, IL, USA to Saint Louis, MO, USA from $13: 5 ways by bus, train, flight or car
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How to Get from Mattoon to Saint Louis: Cheapest, Fastest and Best Way
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Get detailed, step-by-step directions below for your trip from Mattoon to Saint Louis with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

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Traveling From Mattoon to Saint Louis
Traveling from Mattoon to Saint Louis offers a refreshing shift from the quiet charm of a small town to the vibrant energy of a major city.
Best Neighbourhoods in Saint Louis
Saint Louis boasts a variety of neighborhoods, each with distinct character.
Best Times To Visit Saint Louis's Attractions
Timing your visit can greatly enhance your experience in Saint Louis's attractions.
Saint Louis Weather: What to Expect Year-Round
Saint Louis experiences a humid subtropical climate, with hot summers and cool winters. Spring and fall are ideal times to visit, offering comfortable temperatures that enhance outdoor activities and sightseeing.
Dining Recommendation
In Saint Louis, don't miss the chance to try the famous toasted ravioli at Tony's in the Hill neighborhood, where this rich, breaded pasta dish comes filled with savory meat and is served with marinara sauce. The lively ambiance and use of locally sourced ingredients create a dining experience that stands in stark contrast to the more traditional fare you might find in Mattoon.
Mattoon - Saint Louis operators
Explore transport companies operating between Mattoon and Saint Louis, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Train from Mattoon Amtrak Station to Carbondale
Train from Mattoon Amtrak Station to Champaign-Urbana
Train from Bloomington-Normal to St. Louis
Bus from Carbondale to St. Louis
Bus from Champaign Intermodal Trans Ctr to St. Louis Bus Station
Bus from Champaign, IL to Bloomington-Normal
Bus from Carbondale Train Station to St. Louis Bus Station
Bus from Champaign Intermodal Trans Ctr to St. Louis Bus Station
Other from Champaign, IL to Bloomington Normal, IL
Frequently asked questions
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Trips from Mattoon
Trips to Champaign
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