Lexington, KY, USA to Saint Louis, MO, USA from $50: 9 ways by bus, train, flight or car

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How to Get from Lexington to Saint Louis: Cheapest, Fastest and Best Way

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$50 - PlaneBest price

553 kmDistance

5h 44m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Lexington to Saint Louis with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

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Traveling From Lexington to Saint Louis

The journey from Lexington to Saint Louis offers a shift from the charming, horse-friendly atmosphere of Kentucky to the vibrant, urban energy of Missouri.

Best Neighbourhoods in Saint Louis

Saint Louis boasts diverse neighborhoods, each with its own charm and attractions.

The Delmar Loop

• Trendy shops and restaurants thrive here.

• Known for vibrant cultural events.

Soulard

• Home to a historic French market.

• Famous for its lively Mardi Gras celebration.

Carondelet

• Features beautiful parks along the Mississippi River.

• Rich in historical architecture and charm.

Best Times To Visit Saint Louis's Attractions

Timing your visits can greatly enhance your experience in Saint Louis.

St. Louis Zoo

Early mornings on weekdays offer fewer crowds and active animals.

Gateway Arch

Visit during weekday afternoons for shorter lines and serene views.

Forest Park

Spring and fall mornings provide beautiful scenery and fewer visitors.

Saint Louis Weather: What to Expect Year-Round

Saint Louis experiences four distinct seasons, with hot summers and chilly winters influencing your travel plans. Spring and fall tend to be the most pleasant times to visit, offering mild temperatures that enhance your enjoyment of outdoor attractions.

Dining Recommendation in Saint Louis

Try the renowned St. Louis-style barbecue at Pappy's Smokehouse, where the slow-cooked, dry-rubbed ribs deliver a smokiness that contrasts sharply with the Southern comfort food of Lexington. The lively atmosphere, complete with blues music and a communal vibe, adds a dynamic experience to your meal that showcases the local culinary scene.

Lexington - Saint Louis operators

Explore transport companies operating between Lexington and Saint Louis, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Plane

Website

aa.com

Plane from Covington to St. Louis

Average Duration

4h 47m

Estimated price

$2038-2039

Plane from Covington to St. Louis

Average Duration

4h 31m

Estimated price

$2038-2039

Plane from Louisville to St. Louis

Average Duration

4h 9m

Estimated price

$500-20310

Plane from Louisville to St. Louis

Average Duration

4h 48m

Estimated price

$501-20330

Plane from Lexington to St. Louis

Average Duration

4h 57m

Estimated price

$502-503

Plane from Lexington to St. Louis

Average Duration

5h 36m

Estimated price

$502-2030

Plane from Covington to St. Louis via Chicago O'Hare

Average Duration

4h 16m

Estimated price

$3351-3353

Plane from Louisville to St. Louis via Chicago O'Hare

Average Duration

4h 33m

Estimated price

$500-20310

Plane from Lexington to St. Louis via Chicago O'Hare

Average Duration

4h 36m

Estimated price

$502-2032

Website

delta.com

Plane from Covington to St. Louis

Average Duration

4h 20m

Estimated price

$1200-1209

Plane from Covington to St. Louis

Average Duration

4h 46m

Estimated price

$1201-2030

Plane from Louisville to St. Louis

Average Duration

5h 6m

Estimated price

$2033-2030

Plane from Lexington to St. Louis via Atlanta

Average Duration

4h 58m

Estimated price

$50-2034

Plane from Lexington to St. Louis via Detroit

Average Duration

5h 38m

Estimated price

$2035-2036

Website

southwest.com

Plane from Covington to St. Louis

Average Duration

4h 22m

Estimated price

$505-12080

Plane from Louisville to St. Louis

Average Duration

4h 4m

Estimated price

$501-506

Plane from Louisville to St. Louis via Atlanta

Average Duration

5h 25m

Estimated price

$507-12000

Plane from Columbus to St. Louis

Average Duration

1h 26m

Estimated price

$508-509

Plane from Columbus to St. Louis via Chicago Midway

Average Duration

3h 35m

Estimated price

$3350-2037

Plane from Columbus to St. Louis via Nashville

Average Duration

3h 40m

Estimated price

$3351-3352

Bus

Contact phone

+1 214-849-8100

Website

greyhound.com

Bus from Evansville Bus Station to St Louis Bus Station

Average Duration

3h 40m

Estimated price

$3354-3355

Bus from Indianapolis Bus Station to St Louis Bus Station

Average Duration

3h 55m

Estimated price

$3356-3357

Contact phone

+1 800-544-2383

Website

hoosierride.com

Bus from Corydon, IN to Evansville, IN

Average Duration

Estimated price

$0-0

Bus from Louisville, KY to Evansville, IN

Average Duration

Estimated price

$0-0

Contact phone

+1 800-872-7245

Website

amtrak.com

Bus from Louisville, KY to Indianapolis Amtrak Station

Average Duration

Estimated price

$3358-2031

Frequently asked questions

Find out more about the route from Lexington to Saint Louis.

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The cheapest way to travel from Lexington to Saint Louis is by driving. The approximate cost of gas for the round trip is between $60 and $90, depending on the vehicle's fuel efficiency. The journey takes approximately 5 hours and 44 minutes, covering a distance of around 340 miles. It is recommended to plan the trip well in advance and consider any potential toll or parking fees along the way.

The fastest way to travel from Lexington to Saint Louis is to drive to Cincinnati/Northern Kentucky International Airport and then fly to St. Louis. The total travel time is approximately 5 hours and 21 minutes, including driving to the airport, check-in, and flying. The cost of this option ranges from $130 to $290, depending on the airline and the time of booking. It is recommended to check for flight options and prices to find the best deals for this route.

The distance from Lexington to Saint Louis is approximately 315 miles. If you choose to drive, the distance is approximately 343.4 miles. The driving distance may vary depending on the route taken and traffic conditions. It is advisable to consult a navigation app or map for the most accurate and up-to-date distance information.

The travel time from Lexington to St. Louis is approximately 10 hours and 58 minutes, including any necessary transfers. This duration may vary depending on the specific route taken and the mode of transportation chosen. It is important to factor in any potential delays or traffic conditions when planning your journey.

There are numerous options for accommodation in St. Louis. There are over 326 hotels available to choose from, offering a range of prices and amenities. Prices for hotels in St. Louis start at around $41 per night, depending on the location and type of accommodation. It is recommended to research and book your accommodation in advance to ensure availability and get the best deals.

Yes, you can drive from Lexington to Saint Louis. The driving distance between the two cities is approximately 343 miles. It takes approximately 5 hours and 44 minutes to drive from Lexington to Saint Louis.

American Airlines, United Airlines, Delta, and Southwest Airlines all offer flights between Lexington and Saint Louis. These flights operate from Louisville Airport to St. Louis Airport. It is recommended to check the websites of these airlines for the most up-to-date flight schedules and prices.

The fastest way to get from Lexington to Saint Louis is by plane. However, there is no direct flight from Lexington to St. Louis. The quickest flight with one stopover takes around 3 hours and 5 minutes. Several airlines such as American Airlines, United Airlines, Delta, and Southwest Airlines offer flights from Lexington to St. Louis. The prices for a flight between the two cities typically range from $145 to $305. Overall, traveling by plane will save you considerable time compared to other modes of transportation.

The flight duration from Lexington to Saint Louis varies depending on the number of stopovers. There are no direct flights available, but the quickest route with one stopover takes approximately 3 hours and 5 minutes. However, it's important to note that flight times can vary due to factors such as weather conditions and airline schedules. It's recommended to check with airlines for the most up-to-date flight information before planning your trip.

The cost of a flight from Lexington to Saint Louis can vary depending on factors such as the airline, time of booking, and travel dates. On average, flights between the two cities can range from $145 to $305. It is advisable to book well in advance and to compare prices from different airlines to secure the best deal. Additionally, keep in mind that prices may also change based on availability and seasonality.

The cost of driving from Lexington to Saint Louis can range from $60 to $90. This estimate includes fuel costs for the approximately 5-hour and 44-minute journey. It's important to consider additional expenses such as tolls, parking fees, and potential vehicle maintenance along the way.

Lexington, KY, USA to Saint Louis, MO, USA from $50: 9 ways by bus, train, flight or car

How to Get from Lexington to Saint Louis: Cheapest, Fastest and Best Way

Compare Train, Bus, Flight, and Driving Options

See more options

Traveling From Lexington to Saint Louis

Best Neighbourhoods in Saint Louis

Best Times To Visit Saint Louis's Attractions

Saint Louis Weather: What to Expect Year-Round

Dining Recommendation in Saint Louis

Lexington - Saint Louis operators

Frequently asked questions

Trips from Lexington

Trips to Saint Louis

Popular routes