Columbia, MO, USA to Sikeston, MO, USA from $45: 6 ways by bus, train, flight or car
Compare Travel Options and Prices
How to Get from Columbia to Sikeston: Cheapest, Fastest and Best Way
1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.
Compare Train, Bus, Flight, and Driving Options
Get detailed, step-by-step directions below for your trip from Columbia to Sikeston with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.
See more options
Traveling From Columbia to Sikeston
The drive from Columbia, known for its vibrant college town energy and lush green parks, to Sikeston, famed for its Southern charm and delicious regional cuisine, offers a fascinating contrast in experiences.
Best Neighbourhoods in Sikeston
Sikeston boasts diverse neighborhoods, each with its own charm.
Best Times To Visit Sikeston's Attractions
Navigating Sikeston's attractions at the right times can enhance your experience.
Sikeston Weather: What to Expect Year-Round
Sikeston experiences a humid subtropical climate, characterized by hot summers and mild winters, making spring and fall the best times to explore the area. Being aware of weather conditions can significantly enhance your travel experience, as outdoor activities thrive in pleasant temperatures.
Dining Recommendation in Sikeston
A visit to Sikeston isn't complete without trying the famous St. Louis-style barbecue ribs at Hickory Log Restaurant, which feature a smoky flavor profile that differs from Columbia's more eclectic dining scene. The warm, inviting atmosphere and use of locally sourced ingredients create a one-of-a-kind experience that highlights the region's culinary heritage.
Columbia - Sikeston operators
Explore transport companies operating between Columbia and Sikeston, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Bus from Columbia to St Louis Bus Station
Bus from St Louis Bus Station to Paducah Bus Station
Train from St. Louis to Poplar Bluff Amtrak Station
Train from Jefferson City Amtrak Station to St. Louis
Plane from Columbia (COU) to Marion (MWA)
Plane from Columbia (COU) to Marion (MWA) via Chicago O'Hare
Other from Paducah Bus Station to Sikeston
Other from Columbia to Columbia Airport
Frequently asked questions
Find out more about the route from Columbia to Sikeston.
Trips from Columbia
- Columbia to Sedalia
- Columbia to Hermann
- Columbia to Indianapolis
- Columbia to Springfield
- Columbia to Memphis
- Columbia to Las Vegas
- Columbia to Fayetteville
- Columbia to Tulsa
- Columbia to Kansas City
- Columbia to Saint Louis
- Columbia to Topeka
- Columbia to Branson
- Columbia to Denver
- Columbia to Omaha
- Columbia to Nashville
- Columbia to Wichita
- Columbia to Wisconsin Dells
- Columbia to Louisville
- Columbia to Kirksville
- Columbia to Lexington
- Columbia to Boonville
- Columbia to Milwaukee
- Columbia to Hays
- Columbia to Wentzville
- Columbia to Springfield
- Columbia to Phoenix
- Columbia to Cape Girardeau
- Columbia to Olathe
- Columbia to Farmington
- Columbia to Dallas
- Columbia to Chicago
- Columbia to Austin
- Columbia to California
- Columbia to Chillicothe
- Columbia to Warrensburg
- Columbia to Moberly
- Columbia to Poplar Bluff
- Columbia to Macon
- Columbia to Overland Park
- Columbia to Columbia