1map logoGo to main page

Saint Louis, MO, USA to Key West, FL, USA from $118: 6 ways by bus, train, flight or car

Compare Travel Options and Prices

from
Saint Louis, United States of America
to
Key West, United States of America

How to Get from Saint Louis to Key West: Cheapest, Fastest and Best Way

1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.

$118 by busBest price
2707 kmDistance
5h 59m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Saint Louis to Key West with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

Company
Various
Plane
Average Duration
5h  59m
Estimated price
$174-916
Recommended
Company
Greyhound USA, Palmland Bus Lines, Flixbus USA
Bus
Average Duration
35h  24m
Estimated price
$118-229
Cheapest
route map
Distance: 2707 km
Duration: 5h 59m

See more options

Company
Various
Bus
Average Duration
35h  45m
Estimated price
$153-1740
Company
Various
Bus
Average Duration
35h  40m
Estimated price
$160-312
Company
Various
Plane
Average Duration
10h  59m
Estimated price
$242-475
Company
Various
Drive
Average Duration
23h  17m
Estimated price
$1741-1742
Browse car rentalsExplore flights

Traveling From Saint Louis to Key West

The journey from Saint Louis to Key West offers a striking transition from the vibrant city life and rich history of the Midwest to the laid-back tropical charm and stunning beaches of the Florida Keys.

Best Neighbourhoods in Key West

Key West's neighborhoods offer diverse experiences for every traveler.

Old Town
• Home to historic architecture and lively nightlife.
• Close to attractions like Mallory Square.
New Town
• Features modern amenities and shopping options.
• Offers easy access to local beaches.
Key West Historic District
• Rich in culture with museums and art galleries.
• Scenic streets lined with palm trees and charm.

Best Times To Visit Key West's Attractions

Timing your visits can elevate your Key West experience significantly.

Duval Street
Visit early in the morning or late afternoon for a more relaxed vibe.
Ernest Hemingway Home and Museum
Weekdays in the morning keep the crowds to a minimum.
Sunset Celebration at Mallory Square
Arrive an hour early to secure a good viewing spot.

Key West Weather: What to Expect Year-Round

Key West enjoys a tropical climate with warm temperatures year-round, making it an inviting destination for sun-seekers. The best times to visit are from December to April, when lower humidity and pleasant breezes enhance your travel experience.

Dining in Key West

While Saint Louis is known for barbecue and hearty Midwestern dishes, you shouldn't miss the fresh catch at Blue Heaven, where the relaxed outdoor setting perfectly complements their iconic Key West lobster Benedict. The vibrant flavors of local seafood, paired with tropical ingredients, create a dining experience that brings the essence of island life straight to your plate.

Saint Louis - Key West operators

Explore transport companies operating between Saint Louis and Key West, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Bus Show bus routes
Contact phone
+1 214-849-8100
Website
https://www.greyhound.com/

Bus from St Louis Bus Station to Indianapolis Bus Station

Average Duration
4h 5m
Estimated price
$0-0

Bus from Indianapolis IN to Miami FL

Average Duration
25h 15m
Estimated price
$0-0

Bus from Downtown Miami to Key West

Average Duration
4h 20m
Estimated price
$118-229

Bus from St Louis Bus Station to Atlanta Bus Station

Average Duration
15h 40m
Estimated price
$0-0
Website
palmlandlines.com

Bus from Indianapolis IN to Miami FL

Average Duration
25h 15m
Estimated price
$0-0

Bus from Atlanta GA to Miami FL

Average Duration
13h 55m
Estimated price
$0-0
Contact phone
+1 (855) 626-8585
Website
flixbus.com

Bus from Downtown Miami to Key West

Average Duration
4h 20m
Estimated price
$118-118

Bus from Atlanta Bus Station to Orlando

Average Duration
9h
Estimated price
$0-0

Bus from Orlando to Miami Airport Station

Average Duration
4h 10m
Estimated price
$0-0

Bus from Miami Airport Station to Key West

Average Duration
3h 55m
Estimated price
$0-0
Plane Show flights
Website
aa.com

Plane from St. Louis Airport to Key West Airport

Average Duration
5h 13m
Estimated price
$1747-1749

Plane from St. Louis Airport to Key West Airport

Average Duration
5h 53m
Estimated price
$1747-1749
Website
delta.com

Plane from St. Louis Airport to Key West Airport

Average Duration
4h 41m
Estimated price
$160-9162
Website
allegiantair.com

Plane from MidAmerica St. Louis to Key West Airport

Average Duration
11h 50m
Estimated price
$9160-9161

Saint Louis to Key West: Overview of Bus, Train, Flight, and Car Trips

Traveling between Saint Louis and Key West offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.

🚗 Embark on an unforgettable road trip from Saint Louis to Key West covering a distance of 1381 miles with approximately 23 hours and 17 minutes of driving time ahead. 💰 The cost of this scenic journey ranges from $250 to $370 by car, offering a budget-friendly option to explore the vibrant sights and sounds from the heartland of America to the southernmost point of the continental U.S.
Average price
$250 - $370
🛫 Traveling from Saint Louis to Key West by plane involves a one-stop flight that typically takes around 4 hours and 34 minutes. Both Delta and American Airlines provide options for this route. 🌴 Upon arrival in Key West Airport, it takes approximately 5 hours and 59 minutes to reach Saint Louis. The journey offers a mix of flight times and stopovers, depending on the airline and schedule chosen. 💸 Prices for flights between Key West and Saint Louis can range from $174 to $916, offering travelers a variety of options to suit their budget and preferences.
Departure Point
St. Louis Airport
Arrival Point
Key West Airport. The quickest flight takes 4h 34m and has one stopover
Useful tips for plane travellers
• Be prepared for your layover: Most flights from St. Louis to Key West include a stopover, usually in Atlanta or Miami, where you might need to switch terminals. Familiarize yourself with the airport layout beforehand to make your connection smoother.
• Upon arrival at Key West International Airport (EYW), you'll likely find the airport's small size makes navigation easy; however, be ready for potential delays due to weather or limited staff. Once you land, check the signage for baggage claim and exit towards the taxi area, but don't forget to turn on your maps to familiarize yourself with your route into the city.
• Taxi fares from Key West Airport to the city center typically range from $15 to $25, depending on your exact destination and the time of day. Consider pre-arranging a taxi service through local companies like Uber or Key West Taxis for better peace of mind upon arrival.
🚌 Embark on an adventurous bus journey from St. Louis to Key West, with convenient services departing from St. Louis Bus Station, including transfers in Indianapolis IN and Downtown Miami. The total travel time for this unique route is approximately 35 hours and 24 minutes. 💸 Prices for bus tickets between Key West and St. Louis range from $118 to $229, offering budget-friendly options for travelers looking to explore the vibrant city of Key West from the heart of the Midwest.
Departure Point
St Louis Bus Station
Arrival Point
Key West station

Frequently asked questions

Find out more about the route from Saint Louis to Key West.

Or choose the category:
The distance between St. Louis and Key West is 1096 miles, with a road distance of 1380.7 miles. The typical travel time by plane from St. Louis to Key West is 6 hours and 49 minutes. If you choose to drive, it would take approximately 23 hours and 17 minutes to travel from Key West to St. Louis by car. Alternatively, taking a bus would require around 35 hours and 24 minutes to reach Key West from St. Louis.
The most cost-effective and time-efficient transportation option for traveling from Saint Louis to Key West is by flying. It takes approximately 6 hours and 49 minutes to reach Key West by plane, making it the fastest option. However, it is important to note that flying can be more expensive, with prices ranging from $300 to $850. Alternatively, taking a bus is the cheapest way to travel, costing between $110 and $230, but it is also the most time-consuming, taking approximately 35 hours and 24 minutes.
The prices for traveling from Saint Louis to Key West by bus vary between $118 and $229. The actual price depends on factors such as the time of booking, season, and availability. It is recommended to check with different bus operators to find the best price for your travel dates. Additionally, prices for other modes of transportation such as plane or car may vary, so it's advisable to compare prices and travel times before making a decision.
To travel from Saint Louis to Key West without using public transportation, you can drive. The driving distance is approximately 1381 miles, which takes around 23 hours and 17 minutes. The cost of the trip by car will vary, with estimates ranging from $250 to $370.
The best way to travel from Saint Louis to Key West without a car is to take a bus. The bus journey typically takes around 32 hours and 10 minutes and includes a transfer in Atlanta. The cost of the bus ticket can range from $140 to $380. This option allows you to sit back, relax, and enjoy the scenic views along the way while avoiding the hassle of driving.
Yes, there is a way to travel between Saint Louis and Key West but there is no direct link. The most convenient option is to fly, which takes around 6 hours and 49 minutes. If you prefer driving, it would take approximately 23 hours and 17 minutes by car, covering a road distance of 1380.7 miles. Another option is taking a bus, with a journey time of around 35 hours and 24 minutes, including transfers.
The flight duration between Saint Louis and Key West typically takes around 4 hours and 20 minutes with one stopover. However, there are no direct flights available, so travelers will have to make a layover. The cost of flights between Key West and Saint Louis can vary, with prices ranging from $304 to $806, depending on the airline, timing, and availability. It is recommended to compare prices and book in advance to find the best deals.
There are numerous accommodation options available near Key West. With over 466 hotels to choose from, travelers are sure to find something that suits their needs and preferences. Prices for hotels in Key West start at $142 per night, making it possible to find options to fit various budgets. Whether you're looking for luxury resorts, charming bed and breakfasts, or budget-friendly hotels, Key West has a variety of options to choose from.

Trips from Saint Louis

Trips to Key West