Knoxville, TN, USA to Louisville, KY, USA from $45: 5 ways by bus, train, flight or car
Compare Travel Options and Prices
How to Get from Knoxville to Louisville: Cheapest, Fastest and Best Way
1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.
Compare Train, Bus, Flight, and Driving Options
Get detailed, step-by-step directions below for your trip from Knoxville to Louisville with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.
See more options
Traveling From Knoxville to Louisville
The journey from Knoxville to Louisville takes you from the scenic beauty of the Great Smoky Mountains to the vibrant urban culture of the Derby City, offering a delightful contrast in experiences.
Best Neighborhoods in Louisville
Louisville boasts diverse neighborhoods, each offering its own charm and attractions.
Best Times To Visit Louisville's Attractions
Timing your visits can elevate your experience at Louisville's top sights.
Louisville Weather: What to Expect Year-Round
Louisville experiences a humid subtropical climate with four distinct seasons, making spring and fall the best times for favorable weather and outdoor activities. Understanding how temperature and precipitation fluctuate throughout the year can help shape your travel plans and influence what to pack.
Louisville Dining Recommendation
Don’t miss the chance to savor the famous Hot Brown at the Brown Hotel, a rich open-faced turkey sandwich smothered in Mornay sauce, perfectly capturing Louisville’s rich culinary tradition. Unlike Knoxville's Southern comfort foods, this dish introduces a sophisticated twist with local ingredients, providing a dining atmosphere that blends history and innovation.
Knoxville - Louisville operators
Explore transport companies operating between Knoxville and Louisville, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Plane from Knoxville (TYS) to Louisville (SDF)
Plane from Knoxville (TYS) to Louisville (SDF)
Plane from Knoxville (TYS) to Louisville (SDF)
Plane from Knoxville (TYS) to Lexington (LEX)
Plane from Knoxville (TYS) to Lexington (LEX)
Plane from Knoxville (TYS) to Louisville (SDF)
Plane from Knoxville (TYS) to Louisville (SDF)
Plane from Knoxville (TYS) to Lexington (LEX)
Plane from Knoxville (TYS) to Louisville (SDF)
Plane from Knoxville (TYS) to Louisville (SDF)
Plane from Knoxville (TYS) to Lexington (LEX)
Bus from Greeneville to Nashville Bus Station
Bus from Nashville to Louisville, KY
Bus from Nashville to La Tropicana - Louisville, KY
Knoxville to Louisville: Overview of Bus, Train, Flight, and Car Trips
Traveling between Knoxville and Louisville offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.
Useful tips for plane travellers
Frequently asked questions
Find out more about the route from Knoxville to Louisville.
Trips from Knoxville
- Knoxville to Chicago
- Knoxville to Gatlinburg
- Knoxville to New Orleans
- Knoxville to Crossville
- Knoxville to New York City
- Knoxville to Memphis
- Knoxville to Roanoke
- Knoxville to Indianapolis
- Knoxville to Raleigh
- Knoxville to Cincinnati
- Knoxville to Bristol
- Knoxville to Orlando
- Knoxville to Sevierville
- Knoxville to Columbia
- Knoxville to Seattle
- Knoxville to Asheville
- Knoxville to Destin
- Knoxville to Phoenix
- Knoxville to Birmingham
- Knoxville to Pensacola
- Knoxville to Greenville
- Knoxville to Denver
- Knoxville to Boston
- Knoxville to Pigeon Forge
- Knoxville to Johnson City
- Knoxville to Atlanta
- Knoxville to Lexington
- Knoxville to Detroit
- Knoxville to Tuscaloosa
- Knoxville to Fort Lauderdale
- Knoxville to Pittsburgh
- Knoxville to Dallas
- Knoxville to Baltimore
- Knoxville to Nashville
- Knoxville to Miami
- Knoxville to Charlotte
- Knoxville to Omaha
- Knoxville to Chattanooga
- Knoxville to North Myrtle Beach
- Knoxville to Navarre Beach
Trips to Louisville
- Chicago to Louisville
- Boston to Louisville
- Owensboro to Louisville
- Nashville to Louisville
- Cincinnati to Louisville
- Lexington to Louisville
- South Bend to Louisville
- Indianapolis to Louisville
- Richmond to Louisville
- Columbus to Louisville
- Pittsburgh to Louisville
- Milwaukee to Louisville
- Asheville to Louisville
- Kansas City to Louisville
- Raleigh to Louisville
- Philadelphia to Louisville
- Paducah to Louisville
- Charleston to Louisville
- New Orleans to Louisville
- Miami to Louisville
- Newark to Louisville
- Memphis to Louisville
- Atlanta to Louisville
- Dallas to Louisville
- Charlotte to Louisville
- Saint Louis to Louisville
- Burlington to Louisville
- Frankfort to Louisville
- Laurel to Louisville
- Radcliff to Louisville
- Corbin to Louisville
- Charleston to Louisville
- Pikeville to Louisville
- Huntsville to Louisville
- Chattanooga to Louisville
- London to Louisville
- New Albany to Louisville
- Birmingham to Louisville
- Hebron to Louisville
- Springfield to Louisville