Charleston, WV, USA to Saint Louis, MO, USA from $33: 5 ways by bus, train, flight or car
Compare Travel Options and Prices
How to Get from Charleston to Saint Louis: Cheapest, Fastest and Best Way
1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.
Compare Train, Bus, Flight, and Driving Options
Get detailed, step-by-step directions below for your trip from Charleston to Saint Louis with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.
See more options
Traveling From Charleston to Saint Louis
The journey from Charleston, known for its charming Southern ambiance and coastal allure, to Saint Louis, a vibrant hub of Midwestern culture and iconic architecture, offers travelers a striking contrast of experiences that reflect two distinct American lifestyles.
Best Neighbourhoods in Saint Louis
Saint Louis boasts diverse neighborhoods, each with its own charm and offerings.
Best Times To Visit Saint Louis's Attractions
Navigating the best times to explore Saint Louis's attractions enhances your experience and reduces wait times.
Saint Louis Weather: What to Expect Year-Round
Saint Louis experiences a humid subtropical climate, with hot summers and cold winters, making spring and fall ideal for comfortable outdoor activities. Understanding the seasonal weather patterns can significantly enhance your travel experience as it influences both crowd sizes and available attractions.
Dining Recommendation in Saint Louis
For a delightful contrast to Charleston’s seafood-rich cuisine, try the toasted ravioli at Anthony's Italian Restaurant, where this local favorite reflects Saint Louis’s Italian heritage with a crispy exterior and savory filling. The lively atmosphere and accessibility to locally sourced ingredients create a dining experience that celebrates regional flavors distinct from the Lowcountry.
Charleston - Saint Louis operators
Explore transport companies operating between Charleston and Saint Louis, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Plane from Charleston (CRW) to St. Louis (STL)
Plane from Charleston (CRW) to St. Louis (STL)
Plane from Charleston (CRW) to St. Louis (STL)
Train from Charleston, WV to Chicago Union Station
Train from Chicago Union Station to St. Louis
Train from Charleston, WV to St. Louis
Bus from Indianapolis Bus Station to St Louis Bus Station
Bus from Cambridge to St Louis Bus Station
Bus from Charleston, WV to St Louis Bus Station
Bus from Charleston, WV to Cambridge
Other from Charleston to St. Louis
Frequently asked questions
Find out more about the route from Charleston to Saint Louis.
Trips from Charleston
- Charleston to Nashville
- Charleston to Snowshoe
- Charleston to Wytheville
- Charleston to Louisville
- Charleston to Chicago
- Charleston to Lexington
- Charleston to Roanoke
- Charleston to Charlotte
- Charleston to Pittsburgh
- Charleston to Cincinnati
- Charleston to Wheeling
- Charleston to Cleveland
- Charleston to Raleigh
- Charleston to Morgantown
- Charleston to Indianapolis
- Charleston to Elkview
- Charleston to Martinsburg
- Charleston to Clarksburg
- Charleston to Richmond
- Charleston to Ashland
- Charleston to Baltimore
- Charleston to Bluefield
- Charleston to Wilmington
- Charleston to Destin
- Charleston to Fort Lauderdale
- Charleston to Washington
- Charleston to Philadelphia
- Charleston to Miami
- Charleston to Tampa
- Charleston to Austin
- Charleston to Beckley
- Charleston to Columbus
- Charleston to Milton
- Charleston to Parkersburg
- Charleston to Berkeley Springs
- Charleston to Fairmont
- Charleston to Huntington
- Charleston to Nitro
- Charleston to Daytona Beach
- Charleston to Myrtle Beach
Trips to Saint Louis
- Houston to Saint Louis
- Omaha to Saint Louis
- New York City to Saint Louis
- Kansas City to Saint Louis
- Chicago to Saint Louis
- Dallas to Saint Louis
- Memphis to Saint Louis
- Detroit to Saint Louis
- Iowa City to Saint Louis
- Indianapolis to Saint Louis
- Little Rock to Saint Louis
- Cleveland to Saint Louis
- Des Moines to Saint Louis
- Austin to Saint Louis
- Cincinnati to Saint Louis
- Branson to Saint Louis
- Paducah to Saint Louis
- Poplar Bluff to Saint Louis
- Wichita to Saint Louis
- San Diego to Saint Louis
- Chattanooga to Saint Louis
- Louisville to Saint Louis
- Columbia to Saint Louis
- Carbondale to Saint Louis
- Rolla to Saint Louis
- Maryland Heights to Saint Louis
- Champaign to Saint Louis
- Kansas City to Saint Louis
- Joplin to Saint Louis
- Springfield to Saint Louis
- Jefferson City to Saint Louis
- Bloomington to Saint Louis
- Overland Park to Saint Louis
- Peoria to Saint Louis
- Cape Girardeau to Saint Louis
- Chesterfield to Saint Louis
- Pittsburgh to Saint Louis
- Farmington to Saint Louis
- Springfield to Saint Louis
- Eureka to Saint Louis