Cusco to Santiago from $161: 4 ways by bus, train, flight or car

🚗 Embark on an epic road trip from the ancient city of Cusco to the vibrant metropolis of Santiago covering a distance of 1799 miles. Enjoy the diverse landscapes, from the majestic Andes Mountains to the arid deserts, as you journey through this South American adventure. 💸 Plan your budget wisely as the cost of driving from Cusco to Santiago by car typically ranges from $430 to $650, depending on factors such as fuel prices, tolls, and accommodation along the way. Consider including stops in charming towns like Arequipa and La Serena to break up the long drive and immerse yourself in local culture.

🛫 Flying from Cusco to Santiago is a convenient option with the quickest direct flight taking only 3 hours and 20 minutes, offered by airlines like JetSMART, Sky Airline, and LATAM Chile. 🌎 The journey from Cusco to Santiago by plane typically takes around 6 hours and 23 minutes, providing travelers with a relatively quick way to reach their destination in Chile. 💸 Flight prices between Santiago and Cusco can range from $161 to $484, giving passengers a variety of options based on their budget and preferences.

🌄 The total travel time, including transfers, is approximately 43 hours and 3 minutes, offering a unique opportunity to explore multiple cities along the way.