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Medellin, Antioquia to Santiago, Santiago Metropolitan from $123: 7 ways by bus, train, flight or car

Compare Travel Options and Prices

from
Medellin, Colombia
to
Santiago, Chile

How to Get from Medellin to Santiago: Cheapest, Fastest and Best Way

1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.

$123 by busBest price
4472 kmDistance
9h 29m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Medellin to Santiago with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

Company
various
Plane
Average Duration
9h  29m
Estimated price
$218-639
Recommended
Company
various
Bus
Average Duration
123h  3m
Estimated price
$123-657
Cheapest
route map
Distance: 4472 km
Duration: 9h 29m

See more options

Company
various
Bus
Taxi
Average Duration
99h  7m
Estimated price
$141-2180
Company
various
Taxi
Plane
Average Duration
12h  8m
Estimated price
$291-534
Company
various
Plane
Average Duration
9h  52m
Estimated price
$319-630
Company
various
Bus
Average Duration
104h  20m
Estimated price
$2181-2182
Company
various
Drive
Average Duration
83h  11m
Estimated price
$2183-2184
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Traveling From Medellin to Santiago

The route from Medellin to Santiago offers a fascinating contrast between Medellin’s vibrant culture and lush landscapes and Santiago’s modern skyline and rich history.

Best Neighbourhoods in Santiago

Santiago boasts diverse neighborhoods, each with its own charm and vibe.

Bellavista
• Vibrant street art and bohemian atmosphere.
• Plenty of bars and dining options.
Las Condes
• Upscale shopping and luxury hotels.
• Home to stunning parks and skyscrapers.
Lastarria
• Artsy vibe with theaters and galleries.
• Cozy cafes and local craft shops.

Best Times To Visit Santiago's Attractions

Timing your visits to Santiago’s attractions can greatly enhance your experience.

Cerro San Cristóbal
Mornings offer cooler weather and fewer visitors, ideal for panoramic views.
Plaza de Armas
Weekday afternoons feature local life without the weekend crowds.
Museo Chileno de Arte Precolombino
Visit early in the day to enjoy the exhibits with less foot traffic.

Santiago Weather: What to Expect Year-Round

Santiago experiences a Mediterranean climate with warm, dry summers and mild, rainy winters, making spring (September to November) and autumn (March to May) the ideal times to visit. Understanding the seasonal variations in weather can significantly impact your travel plans, from outdoor activities to cultural events.

Dining Recommendation in Santiago

Try the famous Pastel de Choclo at La Fama, a delightful corn pie that showcases Chilean flavors with a delicious blend of corn, meat, and olives. This dish offers a different culinary experience than Medellin’s vibrant street food, highlighting local ingredients and a cozy, inviting atmosphere that captures the essence of Santiago.

Medellin - Santiago operators

Explore transport companies operating between Medellin and Santiago, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Bus Show bus routes
Contact phone
018000119019
Website
flotamagdalena.com

Bus from Medellín to Pasto

Average Duration
15h
Estimated price
1232-1233
Contact phone
+51 967 884526
Website
lineasdelosandes.com

Bus from Cúcuta to Terminal San Borja

Average Duration
4h 11m
Estimated price
1236-6394

Bus from Rumichaca to Gran Terminal Terrestre Plaza Norte

Average Duration
31h 22m
Estimated price
1235-6391
Contact phone
0810 122 1122
Website
andesmar.com

Bus from Gran Terminal Terrestre Plaza Norte to Terminal San Borja

Average Duration
49h 5m
Estimated price
1237-1238
Contact phone
0057 315 4525691

Bus from Terminal Norte to Terminal de Transporte Cali

Average Duration
9h
Estimated price
6570-0
Contact phone
+57 601 4249090
Website
bolivariano.com.co

Bus from Terminal Norte to Terminal de Transporte Cali

Average Duration
10h
Estimated price
6571-6572

Bus from Terminal de Transporte Cali to Ipiales

Average Duration
11h
Estimated price
6573-1234

Bus from Medellín to Cúcuta

Average Duration
15h
Estimated price
6574-1235
Plane Show flights
Website
avianca.com

Plane from Medellin Jose Marie Cordova (MDE) to Santiago (SCL)

Average Duration
8h 7m
Estimated price
6391-6392
Website
latam.com

Plane from Medellin Jose Marie Cordova (MDE) to Santiago (SCL)

Average Duration
7h 41m
Estimated price
6391-2183
Website
jetsmart.com

Plane from Medellin Jose Marie Cordova (MDE) to Santiago (SCL)

Average Duration
6h 8m
Estimated price
6397-0
all-pages.other Show other routes
Contact phone
0584
Website
tax-individual.com.co

Other from Medellín to Pereira

Average Duration
3h 34m
Estimated price
65755-6577

Medellin to Santiago: Overview of Bus, Train, Flight, and Car Trips

Traveling between Medellin and Santiago offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.

🚗 Embark on an epic road trip from Medellín to Santiago, covering a distance of 3901 miles. The journey offers breathtaking landscapes and diverse cultures along the way. 💸 Prices for the drive from Medellin to Santiago can range from $750 to $1200, making it a budget-friendly option for adventurers seeking a unique travel experience. ⏱️ Plan for a thrilling 3 days and 11 hours on the road as you traverse scenic routes and make unforgettable memories on this unforgettable journey from Colombia to Chile.
Average price
$750 - $1200
🛫 Get ready for a smooth and efficient journey from Medellin to Santiago! The quickest flight takes just 6 hours and 8 minutes, ensuring you reach your destination in good time. 💸 Prices for flights between Santiago and Medellin can range from $218 to $639, offering a range of options to suit different budgets for your travels between these vibrant South American cities.
Departure Point
Medellin Jose Marie Cordova Airport
Arrival Point
Santiago Airport
🚌 The journey from Medellin to Santiago by bus takes approximately 30 to 35 hours. 💰 The prices for a bus ticket between Santiago and Medellin can range from $123 to $657, depending on the class of service and the time of booking.

Frequently asked questions

Find out more about the route from Medellin to Santiago.

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The distance between Medellín and Santiago is 2779 miles. The road distance is slightly longer at 3901 miles. If you choose to travel by air, it takes approximately 9 hours and 21 minutes to reach Santiago from Medellin. However, if you prefer a combination of bus and flight, the travel time increases to 13 hours and 48 minutes. Unfortunately, there is no available information on the travel time by car or bus from Santiago to Medellin.
The most cost-effective option for traveling from Medellin to Santiago is by bus, as it is generally cheaper with prices ranging from $210 to $400. However, it is important to note that this option takes a significant amount of time, usually around 4 days and 22 hours. If time is of the essence, the fastest and most time-efficient option is to fly, with a travel time of approximately 9 hours and 21 minutes. Bear in mind that airline ticket prices can range from $210 to $600.
The prices for a bus between Santiago and Medellin range from $119 to $655. These prices may vary depending on factors such as the class of the bus, the level of comfort, and any additional services offered. It is advisable to check with different bus companies to find the best price for your travel needs.
To get from Medellin to Santiago without using public transportation, you can choose to drive. The driving distance between Medellin and Santiago is approximately 3901 miles, which would take around 3 days and 11 hours without accounting for rest breaks. There may be some fluctuation in prices, but the costs to rent a car and drive to Santiago from Medellin range from $750 to $1200.
The best way to travel from Medellín to Santiago without a car is to take a bus. The journey takes approximately 5 days and 3 hours, with ticket prices ranging from $110 to $700. Buses offer a comfortable and affordable option for long-distance travel between the two cities, allowing you to enjoy the scenic views and make stops along the way.
The flight from Medellin to Santiago typically takes around 6 hours and 8 minutes. The cost of the flight can vary between $214 and $567, depending on the airline and the time of booking. It is recommended to compare prices from different airlines and book in advance to secure the best deal. Overall, flying is the quickest and most convenient mode of transportation between the two cities.
There are plenty of options for accommodation near Santiago. With over 1007 hotels to choose from, travelers can find a range of prices starting at $48 per night. Whether you're looking for luxury hotels, budget-friendly options, or something in between, Santiago offers a variety of choices to suit different preferences and budgets. It is recommended to book in advance to secure the best deals and availability.

Trips from Medellin

Trips to Santiago