Mexico City, Federal District to Santiago, Santiago Metropolitan from $250: 3 ways by bus, train, flight or car
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How to Get from Mexico City to Santiago: Cheapest, Fastest and Best Way
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Compare Train, Bus, Flight, and Driving Options
Get detailed, step-by-step directions below for your trip from Mexico City to Santiago with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.
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Traveling From Mexico City to Santiago
Traveling from Mexico City to Santiago reveals a striking contrast between bustling urban life and a more laid-back, picturesque atmosphere, where vibrant street culture meets stunning natural landscapes.
Best Neighbourhoods in Santiago
Santiago offers diverse neighborhoods, each with distinct character and charm.
Best Times To Visit Santiago's Attractions
Timing your visits to Santiago’s attractions can significantly enhance your experience.
Santiago Weather: What to Expect Year-Round
Santiago boasts a Mediterranean climate, characterized by hot, dry summers and mild, rainy winters, making it an appealing destination year-round. The spring and fall months offer pleasant temperatures and fewer crowds, enhancing your overall travel experience.
Dining Recommendation in Santiago
Try the iconic Chilean dish called empanada de pino at La Vega, where savory fillings of beef, olives, and hard-boiled egg are encased in flaky pastry, offering a satisfying contrast to the vibrant flavors of tacos or enchiladas in Mexico City. The local ingredients and relaxed ambiance at La Vega create a unique dining experience that highlights the rich culinary traditions of Chile.
Mexico City - Santiago operators
Explore transport companies operating between Mexico City and Santiago, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Plane from Mexico City (MEX) to Santiago (SCL)
Plane from Mexico City (MEX) to Santiago (SCL)
Plane from Mexico City (MEX) to Santiago (SCL)
Plane from Mexico City (MEX) to Santiago (SCL)
Plane from Mexico City (MEX) to Santiago (SCL)
Plane from Mexico City Santa Lucia Apt (NLU) to Santiago (SCL)
Plane from Mexico City Santa Lucia Apt (NLU) to Santiago (SCL)
Mexico City to Santiago: Overview of Bus, Train, Flight, and Car Trips
Traveling between Mexico City and Santiago offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.
Frequently asked questions
Find out more about the route from Mexico City to Santiago.
Trips from Mexico City
- Mexico City to Puebla
- Mexico City to Toluca
- Mexico City to Guanajuato
- Mexico City to Puerto Vallarta
- Mexico City to Oaxaca
- Mexico City to Morelia
- Mexico City to Cuernavaca
- Mexico City to Tijuana
- Mexico City to Acapulco
- Mexico City to Guadalajara
- Mexico City to Valle de Bravo
- Mexico City to Monterrey
- Mexico City to San Miguel de Allende
- Mexico City to New York City
- Mexico City to Panama City
- Mexico City to Nuevo Laredo
- Mexico City to Los Angeles
- Mexico City to Miami
- Mexico City to Taxco de Alarcon
- Mexico City to Sayulita
- Mexico City to Teotihuacan
- Mexico City to Cancun
- Mexico City to Puerto Escondido (Oaxaca)
- Mexico City to Ciudad Juárez
- Mexico City to Maravatío
- Mexico City to Tepoztlán
- Mexico City to Tequesquitengo
- Mexico City to Huixquilucan de Degollado
- Mexico City to Denver
- Mexico City to Hermosillo
- Mexico City to San Luis Potosí
- Mexico City to Trelew
- Mexico City to Houston
- Mexico City to Silao
- Mexico City to Tulsa
- Mexico City to Oakland
- Mexico City to Palermo
- Mexico City to Cali
- Mexico City to Mexico City
- Mexico City to La Florida
Trips to Santiago
- Lima to Santiago
- San Pedro de Atacama to Santiago
- Montevideo to Santiago
- Buenos Aires to Santiago
- Seattle to Santiago
- Atlanta to Santiago
- Boston to Santiago
- Mendoza to Santiago
- Valparaíso to Santiago
- La Serena to Santiago
- Los Angeles to Santiago
- San Antonio (Valparaiso) to Santiago
- Puerto Natales to Santiago
- El Calafate to Santiago
- Puerto Montt to Santiago
- Medellin to Santiago
- Uyuni to Santiago
- Bogota to Santiago
- Calama to Santiago
- Antofagasta to Santiago
- Melbourne to Santiago
- Cancun to Santiago
- Sydney to Santiago
- San Diego to Santiago
- Denver to Santiago
- Boise to Santiago
- Las Vegas to Santiago
- Washington to Santiago
- New York City to Santiago
- Auckland to Santiago
- Brisbane to Santiago
- Philadelphia to Santiago
- Houston to Santiago
- Easter Island to Santiago
- Chicago to Santiago
- Tijuana to Santiago
- Torres del Paine National Park to Santiago
- Hartford to Santiago
- Salt Lake City to Santiago
- Raleigh to Santiago