Isernia, Molise to Rome, Lazio from $8: 4 ways by bus, train, flight or car

• The primary operator for the Isernia to Rome route is Trenitalia. Onboard, you'll find a catering service offering snacks and beverages, including local wines and coffee options, available directly from the Train Manager. Another operator, Italo, focuses on providing a modern experience, typically with a cafe service in their on-board bistro for refreshments.

• The Trenitalia trains on this route offer several seating options: First Class (Business) provides more spacious seating and complimentary refreshments, while Second Class (Economy) offers standard seating. If traveling with Italo, you'll find seats categorized into Smart, Comfort, and Prima, with Prima offering the most comfort and amenities.

• Upon arrival at Rome Termini, you'll experience a bustling main hub. You can store your luggage at the left luggage office (Deposito Bagagli) located near the entrance. Additionally, you can find restrooms and some showers in the 'Freccia Club' lounge for First Class passengers. For the fastest way to reach the city center, take Metro Line A from Termini, which connects directly to popular areas like Piazza di Spagna and Vatican City.