
Des Moines, IA, USA to Sioux Falls, SD, USA from $74: 4 ways by bus, train, flight or car
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How to Get from Des Moines to Sioux Falls: Cheapest, Fastest and Best Way
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Get detailed, step-by-step directions below for your trip from Des Moines to Sioux Falls with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

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Traveling From Des Moines to Sioux Falls
The journey from Des Moines to Sioux Falls offers a fascinating contrast between the vibrant urban vibe of Iowa's capital and the scenic natural beauty and charming small-town feel of South Dakota.
Best Neighbourhoods in Sioux Falls
Sioux Falls boasts diverse neighborhoods, each offering distinct charm and attractions.
Best Times To Visit Sioux Falls's Attractions
Planning your trip around key attractions can enhance your experience in Sioux Falls.
Sioux Falls Weather: What to Expect Year-Round
Sioux Falls experiences a mix of four distinct seasons, with warm summers and cold winters, making it important to plan your visit accordingly. Spring and fall tend to be the most pleasant times to explore, as mild temperatures can enhance your outdoor experiences.
Dining Recommendation in Sioux Falls
For a taste of Sioux Falls, try the locally sourced bison burger at Falls Overlook Café, which embodies the region's rich agricultural heritage. This dining experience contrasts with Des Moines by showcasing bold, savory flavors in a relaxed atmosphere overlooking the stunning waterfall.
Des Moines - Sioux Falls operators
Explore transport companies operating between Des Moines and Sioux Falls, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Plane from Des Moines (DSM) to Sioux Falls (FSD)
Plane from Des Moines (DSM) to Sioux Falls (FSD) via Minneapolis
Plane from Des Moines (DSM) to Sioux Falls (FSD) via Atlanta
Plane from Des Moines (DSM) to Sioux Falls (FSD) via Chicago O'Hare
Plane from Des Moines (DSM) to Sioux Falls (FSD) via Dallas/Ft.Worth
Plane from Des Moines (DSM) to Sioux Falls (FSD) via Denver
Bus from Des Moines, IA to Omaha, NE
Bus from Omaha, NE to Sioux Falls, SD
Des Moines to Sioux Falls: Overview of Bus, Train, Flight, and Car Trips
Traveling between Des Moines and Sioux Falls offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.
Frequently asked questions
Find out more about the route from Des Moines to Sioux Falls.
Trips from Des Moines
- Des Moines to Chicago
- Des Moines to Ames
- Des Moines to Pella
- Des Moines to Indianola
- Des Moines to Marshalltown
- Des Moines to Osceola
- Des Moines to Newton
- Des Moines to Fort Dodge
- Des Moines to Kansas City
- Des Moines to Waterloo
- Des Moines to Mason City
- Des Moines to Cedar Rapids
- Des Moines to Peoria
- Des Moines to Moline
- Des Moines to Okoboji
- Des Moines to New Orleans
- Des Moines to Minneapolis
- Des Moines to Lincoln
- Des Moines to Milwaukee
- Des Moines to Perry
- Des Moines to Rochester
- Des Moines to New York City
- Des Moines to Nashville
- Des Moines to Seattle
- Des Moines to San Diego
- Des Moines to Las Vegas
- Des Moines to Dallas
- Des Moines to Atlanta
- Des Moines to Indianapolis
- Des Moines to Saint Louis
- Des Moines to Omaha
- Des Moines to Sioux City
- Des Moines to Madison
- Des Moines to Kansas City
- Des Moines to Sigourney
- Des Moines to Iowa City
- Des Moines to Greenfield
- Des Moines to Albia
- Des Moines to Idaho Falls
- Des Moines to Eagle Grove
Trips to Chicago
- Yankton to Sioux Falls
- Chicago to Sioux Falls
- Iowa City to Sioux Falls
- Grand Forks to Sioux Falls
- San Diego to Sioux Falls
- Vermillion to Sioux Falls
- Winnipeg to Sioux Falls
- Minneapolis to Sioux Falls
- Los Angeles to Sioux Falls
- Kansas City to Sioux Falls
- Omaha to Sioux Falls
- Marshall to Sioux Falls
- Madison to Sioux Falls
- Mankato to Sioux Falls
- Bismarck to Sioux Falls
- Seattle to Sioux Falls
- Fargo to Sioux Falls
- Denver to Sioux Falls
- Dallas to Sioux Falls
- Billings to Sioux Falls
- Las Vegas to Sioux Falls
- Houston to Sioux Falls
- Saint Louis to Sioux Falls
- Sioux City to Sioux Falls
- Phoenix to Sioux Falls
- Worthington to Sioux Falls
- Pierre to Sioux Falls
- Norfolk to Sioux Falls
- Watertown to Sioux Falls
- Brookings to Sioux Falls
- Fairmont to Sioux Falls
- Deadwood to Sioux Falls
- Rochester to Sioux Falls
- Aberdeen to Sioux Falls
- Salt Lake City to Sioux Falls
- Rapid City to Sioux Falls
- Mitchell to Sioux Falls
- Mesa to Sioux Falls
- Pipestone to Sioux Falls
- Brandon to Sioux Falls