
Saint Louis, MO, USA to Port St. Lucie, FL, USA from $80: 3 ways by bus, train, flight or car
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How to Get from Saint Louis to Port St. Lucie: Cheapest, Fastest and Best Way
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Traveling From Saint Louis to Port St. Lucie
Embark on a journey where the vibrant energy of Saint Louis gives way to the serene beaches and subtropical charm of Port St. Lucie, offering you a striking contrast between urban excitement and coastal relaxation.
Best Neighbourhoods in Port St. Lucie
Port St. Lucie features diverse neighborhoods that cater to different tastes and preferences.
Best Times To Visit Port St. Lucie's Attractions
Planning your visit to Port St. Lucie’s attractions can enhance your experience significantly.
Port St. Lucie Weather: What to Expect Year-Round
Port St. Lucie enjoys a humid subtropical climate, characterized by warm summers and mild winters, which makes it a pleasant destination year-round. The best times to visit are typically during the winter and early spring months, as the weather enhances outdoor activities and ensures comfortable exploration without the sweltering heat.
Dining Recommendation in Port St. Lucie
For an unforgettable culinary experience, try the fresh seafood dishes at the Grilled Cheese Sandwich Co., particularly their signature lobster grilled cheese, which contrasts sharply with the hearty barbecue offerings you find in Saint Louis. The laid-back coastal atmosphere and emphasis on locally sourced ingredients provide a refreshing twist that highlights the flavors of Florida’s coastline.
Frequently asked questions
Find out more about the route from Saint Louis to Port St. Lucie.
Trips from Saint Louis
- Saint Louis to Carbondale
- Saint Louis to New Orleans
- Saint Louis to Minneapolis
- Saint Louis to Chesterfield
- Saint Louis to Peoria
- Saint Louis to Iowa City
- Saint Louis to Cape Girardeau
- Saint Louis to Kansas City
- Saint Louis to Hannibal
- Saint Louis to Fort Leonard Wood
- Saint Louis to Memphis
- Saint Louis to Dallas
- Saint Louis to Houston
- Saint Louis to Louisville
- Saint Louis to Springfield
- Saint Louis to Omaha
- Saint Louis to Toronto
- Saint Louis to Orlando
- Saint Louis to Chicago
- Saint Louis to Montreal
- Saint Louis to Nashville
- Saint Louis to Indianapolis
- Saint Louis to Nashville
- Saint Louis to Madison
- Saint Louis to Milwaukee
- Saint Louis to Oklahoma City
- Saint Louis to Los Angeles
- Saint Louis to Austin
- Saint Louis to Lincoln
- Saint Louis to Miami
- Saint Louis to Des Moines
- Saint Louis to Key West
- Saint Louis to Lexington
- Saint Louis to San Diego
- Saint Louis to Maryland Heights
- Saint Louis to Philadelphia
- Saint Louis to Columbia
- Saint Louis to Cameron
- Saint Louis to Springfield
- Saint Louis to Addison
Trips to Carbondale
- Sarasota to Port St. Lucie
- West Palm Beach to Port St. Lucie
- Tampa to Port St. Lucie
- Atlanta to Port St. Lucie
- Jacksonville to Port St. Lucie
- Delray Beach to Port St. Lucie
- Fort Lauderdale to Port St. Lucie
- Savannah to Port St. Lucie
- Miami to Port St. Lucie
- Fort Myers to Port St. Lucie
- Orlando to Port St. Lucie
- Daytona Beach to Port St. Lucie
- Boynton Beach to Port St. Lucie
- Lakeland to Port St. Lucie
- Okeechobee to Port St. Lucie
- Sebastian to Port St. Lucie
- Gainesville to Port St. Lucie
- Jupiter to Port St. Lucie
- St. Augustine to Port St. Lucie
- Palm Bay to Port St. Lucie
- Ocala to Port St. Lucie
- Palm Beach Gardens to Port St. Lucie
- Kissimmee to Port St. Lucie
- Lake Worth Beach to Port St. Lucie
- Sunrise to Port St. Lucie
- Sebring to Port St. Lucie
- Vero Beach to Port St. Lucie
- Tallahassee to Port St. Lucie
- Hollywood to Port St. Lucie
- Riverview (Hillsborough County) to Port St. Lucie
- The Villages to Port St. Lucie
- Fort Pierce to Port St. Lucie
- St. Petersburg to Port St. Lucie
- Key West to Port St. Lucie
- Miami Beach to Port St. Lucie
- Naples to Port St. Lucie
- Melbourne to Port St. Lucie
- Boca Raton to Port St. Lucie
- Haines City to Port St. Lucie
- Gainesville to Port St. Lucie