
Saint Louis, MO, USA to Lafayette, LA, USA from $98: 7 ways by bus, train, flight or car
Compare Travel Options and Prices
How to Get from Saint Louis to Lafayette: Cheapest, Fastest and Best Way
1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.
Compare Train, Bus, Flight, and Driving Options
Get detailed, step-by-step directions below for your trip from Saint Louis to Lafayette with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

See more options
Traveling From Saint Louis to Lafayette
The journey from Saint Louis to Lafayette reveals striking contrasts, with the vibrant city life and cultural landmarks of Saint Louis giving way to the laid-back charm and rich Cajun heritage of Lafayette.
Best Neighbourhoods in Lafayette
Lafayette's neighborhoods offer a blend of culture, history, and charm.
Best Times To Visit Lafayette's Attractions
Planning your visit to Lafayette's top spots can enhance your experience.
Lafayette Weather: What to Expect Year-Round
Lafayette experiences a humid subtropical climate, with hot summers and mild winters, making spring and fall the most pleasant times to visit. Understanding the weather can help you pack appropriately and plan activities, enhancing your overall travel experience.
Dining Recommendation in Lafayette
When in Lafayette, don’t miss out on trying gumbo at a local eatery like Prejean's, where the rich and complex flavors celebrate the region’s Cajun roots. This dining experience immerses you in the vibrant atmosphere of Louisiana culture, offering a bold contrast to the barbecue and toasted ravioli synonymous with Saint Louis.
Saint Louis - Lafayette operators
Explore transport companies operating between Saint Louis and Lafayette, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Plane from St. Louis (STL) to Lafayette (LFT)
Plane from St. Louis (STL) to Baton Rouge (BTR)
Plane from St. Louis (STL) to Lake Charles (LCH)
Plane from St. Louis (STL) to Lafayette (LFT)
Plane from St. Louis (STL) to Lafayette (LFT)
Plane from St. Louis (STL) to Baton Rouge (BTR)
Train from St. Louis, MO - Amtrak to Carbondale, IL - Amtrak
Train from Carbondale, IL - Amtrak to New Orleans Union Passenger Terminal
Train from New Orleans Bus Station to Lafayette Transit System
Bus from St Louis Bus Station to Atlanta Bus Station
Bus from Atlanta Bus Station to Lafayette Transit System
Taxi from Lake Charles to Lafayette
Drive from St. Louis to Lafayette
Saint Louis to Lafayette: Overview of Bus, Train, Flight, and Car Trips
Traveling between Saint Louis and Lafayette offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.
Useful tips for plane travellers
Frequently asked questions
Find out more about the route from Saint Louis to Lafayette.
Trips from Saint Louis
- Saint Louis to Carbondale
- Saint Louis to New Orleans
- Saint Louis to Minneapolis
- Saint Louis to Chesterfield
- Saint Louis to Peoria
- Saint Louis to Iowa City
- Saint Louis to Cape Girardeau
- Saint Louis to Kansas City
- Saint Louis to Hannibal
- Saint Louis to Fort Leonard Wood
- Saint Louis to Memphis
- Saint Louis to Dallas
- Saint Louis to Houston
- Saint Louis to Louisville
- Saint Louis to Springfield
- Saint Louis to Omaha
- Saint Louis to Toronto
- Saint Louis to Orlando
- Saint Louis to Chicago
- Saint Louis to Mount Vernon
- Saint Louis to Joplin
- Saint Louis to Nashville
- Saint Louis to Indianapolis
- Saint Louis to Nashville
- Saint Louis to Cleveland
- Saint Louis to Oklahoma City
- Saint Louis to Los Angeles
- Saint Louis to Austin
- Saint Louis to Lincoln
- Saint Louis to Miami
- Saint Louis to Saint Lucia
- Saint Louis to Des Moines
- Saint Louis to Key West
- Saint Louis to Chattanooga
- Saint Louis to Louisiana
- Saint Louis to San Diego
- Saint Louis to Philadelphia
- Saint Louis to Columbia
- Saint Louis to Cameron
- Saint Louis to Springfield
Trips to Carbondale
- New Orleans to Lafayette
- Ruston to Lafayette
- Slidell to Lafayette
- Baton Rouge to Lafayette
- Houston to Lafayette
- Austin to Lafayette
- Shreveport to Lafayette
- Atlanta to Lafayette
- Monroe to Lafayette
- Jackson to Lafayette
- Little Rock to Lafayette
- Gulfport to Lafayette
- Pensacola to Lafayette
- Dallas to Lafayette
- New Iberia to Lafayette
- Crowley to Lafayette
- Opelousas to Lafayette
- Alexandria to Lafayette
- Meridian to Lafayette
- San Antonio to Lafayette
- Hammond to Lafayette
- Denver to Lafayette
- Kinder to Lafayette
- Beaumont to Lafayette
- Eunice to Lafayette
- Youngsville to Lafayette
- Houma to Lafayette
- Miami to Lafayette
- Las Vegas to Lafayette
- Memphis to Lafayette
- Mobile to Lafayette
- Biloxi to Lafayette
- Nashville to Lafayette
- Midland to Lafayette
- Lake Charles to Lafayette
- Rayne to Lafayette
- Leesville to Lafayette
- Houma to Lafayette
- Alexandria to Lafayette
- Pensacola Beach to Lafayette