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Charleston, SC, USA to Knoxville, TN, USA from $65: 3 ways by bus, train, flight or car

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from
Charleston, United States of America
to
Knoxville, United States of America

How to Get from Charleston to Knoxville: Cheapest, Fastest and Best Way

1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.

$65 - OtherBest price
512 kmDistance
4h 43m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Charleston to Knoxville with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

Company
Various
Plane
Average Duration
4h  43m
Estimated price
$132-823
Recommended
Company
N/A
Drive
Average Duration
6h  23m
Estimated price
$65-100
Cheapest
route map
Distance: 512 km
Duration: 4h 43m

See more options

Company
Various
Train
Bus
Taxi
Drive
Drive
Average Duration
18h  4m
Estimated price
$318-648
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Traveling From Charleston to Knoxville

The journey from Charleston to Knoxville offers a fascinating contrast, with Charleston's coastal charm and rich history giving way to Knoxville's vibrant Appalachian culture and stunning mountain views.

Best Neighbourhoods in Knoxville

Knoxville features diverse neighborhoods, each with its own charm and attractions.

Old City
• Vibrant arts scene and live music venues.
• Eclectic shops and eateries enhance the atmosphere.
Market Square
• Bustling area with local farmers' markets.
• Relaxed outdoor seating in a lively environment.
West Knoxville
• Family-friendly parks and recreational facilities.
• Upscale shopping and dining options available.

Best Times To Visit Knoxville's Attractions

Maximizing your experience in Knoxville involves timing your visits to its attractions right.

World’s Fair Park
Visit early in the morning on weekdays for peaceful strolls and fewer crowds.
Knoxville Museum of Art
Fridays during late afternoon often see lighter visitation, enhancing your viewing experience.
Ijams Nature Center
Weekday mornings provide the best chance for solitude in nature trails.

Knoxville Weather: What to Expect Year-Round

Knoxville enjoys a humid subtropical climate with four distinct seasons, making spring and fall the most favorable times to visit for mild temperatures and colorful scenery. Weather conditions can greatly influence your travel plans, from outdoor activities in pleasant spring days to cozy indoor explorations in the winter chill.

Dining Recommendation

Head to Calhoun's on the River for a taste of Knoxville's famous barbecue, where smoky flavors and hearty portions bring a satisfying twist to dining compared to Charleston's coastal seafood. The lively riverside atmosphere, paired with locally sourced ingredients, creates a unique experience that showcases Tennessee's culinary heritage.

Charleston - Knoxville operators

Explore transport companies operating between Charleston and Knoxville, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Plane Show flights
Website
delta.com

Plane from Charleston Airport (CHS) to Knoxville Airport (TYS)

Average Duration
4h 3m
Estimated price
$1322-13220
Website
aa.com

Plane from Charleston Airport (CHS) to Knoxville Airport (TYS)

Average Duration
4h 2m
Estimated price
$132130-1323

Plane from Charleston Airport (CHS) to Knoxville Airport (TYS) via Reagan Washington

Average Duration
4h 24m
Estimated price
$132150-1324
Website
united.com

Plane from Charleston Airport (CHS) to Knoxville Airport (TYS)

Average Duration
4h 45m
Estimated price
$132150-1325
Train Show train routes
Contact phone
+1 800-872-7245
Website
amtrak.com

Train from Charleston Amtrak Station to Selma

Average Duration
3h 54m
Estimated price
$1326-1327

Train from Selma to Charlotte Amtrak Station

Average Duration
4h 18m
Estimated price
$8233-1327
Bus Show bus routes
Contact phone
+1 828-327-2340
Website
hickoryhop.com

Bus from Charlotte Airport to Blowing Rock - Tanger Outlets

Average Duration
2h
Estimated price
$8237-13260
all-pages.other Show other routes
Contact phone
+1-423-725-5988
Website
blackbearresorttn.com

Other from Black Bear Resort to Hot Springs, NC

Average Duration
1h 15m
Estimated price
$0-8238

Charleston to Knoxville: Overview of Bus, Train, Flight, and Car Trips

Traveling between Charleston and Knoxville offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.

🚗 Embark on a scenic road trip from Charleston to Knoxville covering a distance of 375 miles. Enjoy the journey through charming Southern landscapes. 💸 Prices for the trip from Charleston to Knoxville by car range from $65 to $100, providing budget-friendly options for travelers. Plan ahead to snag the best deals on gas and possible pit stops along the way. ⏱️ Expect a driving time of approximately 6 hours and 23 minutes to reach Knoxville from Charleston, giving you the perfect opportunity to explore both cities and enjoy the adventure of the open road.
Average price
$65 - $100
🚉 Embark on a scenic train journey from Charleston to Knoxville! This route spans over 573 miles and involves 3 transfers, offering a unique way to explore the Southeast. 🚉 While the trip takes approximately 1 day and 5 hours, the diverse landscapes and convenient transfers make for a memorable and hassle-free travel experience.
🛫 If you're flying from Charleston to Knoxville be prepared for a journey that includes one stopover. The quickest flight takes around 3 hours and 2 minutes. 🌎 United Airlines, Delta, and American Airlines are three popular choices for flights between Charleston Airport and Knoxville Airport. The total travel time from Charleston to Knoxville by plane is approximately 4 hours and 43 minutes. 💸 The prices for flights between Knoxville and Charleston can vary, ranging from $132 to $823. It's always a good idea to compare different airlines and booking options to find the best deal for your trip.
Departure Point
Charleston Airport
Arrival Point
Knoxville Airport. The quickest flight takes 3h 2m and has one stopover
Useful tips for plane travellers
• When booking your flight from Charleston to Knoxville, keep an eye on layover durations especially if you're connecting through major hubs like Atlanta (Delta) or Charlotte (American); some connections may significantly extend your travel time.
• Upon arrival at McGhee Tyson Airport (TYS) in Knoxville, be prepared to navigate through a smaller terminal, where baggage claim is conveniently located right after security, making it easier to grab your bags and head out without confusion.
• Expect to pay approximately $30-$40 for a taxi ride from McGhee Tyson Airport to downtown Knoxville; consider using ride-share services such as Uber or Lyft for potential savings, especially for larger groups.
🚌 Embark on a scenic bus journey from Charleston to Knoxville spanning 575 miles and requiring 3 transfers. 🌇 Explore Charleston's charming streets before boarding your first bus towards Trident Medical Center, setting the tone for your adventure. 🛣️ Traverse through the picturesque landscapes as you make your way towards Knoxville in a total travel time of 1 day and 12 hours. 🚍 Enjoy the convenience of multiple transfers, each offering a unique glimpse into the region's culture and diversity.

Frequently asked questions

Find out more about the route from Charleston to Knoxville.

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The cheapest way to travel from Charleston to Knoxville is by driving. The estimated cost for the trip is around $65 to $100, depending on fuel prices and vehicle efficiency. The journey takes approximately 6 hours and 23 minutes, allowing you to enjoy the scenic routes and make necessary stops along the way.
The fastest way to travel from Charleston to Knoxville is by flying. There are direct flights available from Charleston International Airport to Knoxville's McGhee Tyson Airport, with a flight duration of approximately 4 hours and 38 minutes. The cost of the flight can range from $180 to $440, depending on the airline and the time of booking. It is advisable to check for flight options and compare prices to find the best deal for your travel.
The distance from Charleston to Knoxville is approximately 318 miles. However, the road distance is about 374.9 miles. This discrepancy is due to the different route options available. The direct driving route takes around 6 hours and 23 minutes, depending on traffic and any stops along the way.
One of the best ways to travel from Charleston to Knoxville without a car is by taking a combination of train and bus. You can take a train from Charleston to Savannah, and then transfer to a bus to travel from Savannah to Knoxville. This journey takes approximately 21 hours and 56 minutes and costs between $30 and $270 depending on the specific route and timing. Another option is to fly from Charleston to Knoxville, which offers a quicker travel time but may be more expensive.
The journey from Charleston to Knoxville takes approximately 4 hours and 38 minutes, including transfers. The fastest way to travel between the two cities is by flying, with several airlines offering direct flights between Charleston International Airport and McGhee Tyson Airport in Knoxville. Alternatively, you can choose to drive, which takes around 6 hours and 23 minutes, or take a bus or train, which have varying travel times depending on the specific route and schedule.
There are several options for accommodation near Knoxville. You can choose from over 196 hotels available in the area. Prices for these hotels start at $44 per night, but can vary depending on the location, amenities, and season. It is recommended to book in advance to secure the best rates and availability for your stay in Knoxville.
Yes, you can drive from Charleston to Knoxville. The driving distance between the two cities is approximately 375 miles. It typically takes about 6 hours and 23 minutes to drive from Charleston to Knoxville, depending on traffic and other factors. Make sure to plan your route and consider any rest stops or meal breaks along the way.
To get to Knoxville from the airport in Charleston you can take a flight, which is the fastest option. There are several airlines that operate flights from Charleston International Airport to McGhee Tyson Airport in Knoxville. The flight duration is approximately 1 hour and 15 minutes. Alternatively, you can also consider renting a car or taking a taxi from the airport to Knoxville, which would take around 4-5 hours depending on traffic conditions. There is no direct train or bus connection between the airport and Knoxville, so flying or driving are the most convenient options.
United Airlines, American Airlines, and Delta offer flights from Charleston Airport to Knoxville Airport. These airlines provide multiple daily flights, allowing for flexibility in travel times. It is recommended to compare prices and schedules from each airline to find the best option for your trip.
The fastest way to get from Charleston to Knoxville by plane is to take a flight. However, there is no direct flight from Charleston Airport to Knoxville Airport. The quickest flight option usually takes approximately 2 hours and 57 minutes with one stopover. Airlines such as United Airlines, American Airlines, and Delta offer flights between Charleston and Knoxville. The prices for flights between the two cities range from $187 to $433.
The flight duration from Charleston to Knoxville can vary depending on the flight itinerary. However, there are no direct flights between Charleston Airport and Knoxville Airport. The quickest flight with one stopover takes approximately 2 hours and 57 minutes. It is advisable to check with airlines for the most accurate and up-to-date flight schedules and durations.
The cost of a flight from Charleston to Knoxville can range from $187 to $433. Prices may vary based on factors such as the airline, the time of booking, and the type of fare chosen. It is advisable to compare prices across different airlines and book in advance to secure the best deal.
The cost of driving from Charleston to Knoxville can range from $65 to $100, depending on factors such as gas prices and the efficiency of your vehicle. This estimate includes fuel costs and tolls, but does not account for additional expenses like meals or accommodations along the way. It's best to plan ahead and budget accordingly to ensure a comfortable and affordable journey.

Trips from Charleston

Trips to Knoxville