Greenville, SC, USA to Knoxville, TN, USA from $462: 4 ways by bus, train, flight or car

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How to Get from Greenville to Knoxville: Cheapest, Fastest and Best Way

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$462 - Bus, flyBest price

272 kmDistance

3h 8m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Greenville to Knoxville with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

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Traveling From Greenville to Knoxville

Traveling from Greenville to Knoxville takes you from the charming small-town feel of Greenville to the vibrant energy of Knoxville, offering an intriguing mix of serene landscapes and lively urban attractions.

Best Neighbourhoods in Knoxville

Knoxville features diverse neighborhoods, each offering distinct experiences for visitors.

Old City

• Historic charm with vibrant nightlife.

• Home to unique boutiques and art galleries.

Market Square

• Central hub for shops and cafes.

• Frequent events and live music performances.

North Knoxville

• Quaint streets lined with historic homes.

• Local eateries showcasing Southern cuisine.

Best Times To Visit Knoxville's Attractions

Planning your visit to Knoxville’s attractions can enhance your experience and enjoyment.

World's Fair Park

Visit early mornings or weekdays for a peaceful stroll and fewer crowds.

Knoxville Museum of Art

Try visiting on the first Friday of the month for special exhibitions and events.

Ijams Nature Center

Optimal times are during weekdays for quieter trails and wildlife viewing.

Knoxville Weather: What to Expect Year-Round

Knoxville features a humid subtropical climate, with warm summers and mild winters that create a pleasant environment for outdoor activities. Spring and fall are generally the best times to explore, as ideal temperatures and vibrant foliage enhance your travel experience.

Dining Recommendation in Knoxville

Try the smoked brisket at Sweet P's Barbeque, which showcases a bold, smoky flavor that sets it apart from the lighter, down-home dishes typical in Greenville. The vibrant atmosphere and use of locally sourced ingredients create a dining experience that reflects Knoxville's rich culinary heritage.

Greenville - Knoxville operators

Explore transport companies operating between Greenville and Knoxville, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Bus Show bus routes

Contact phone

+1 888 358 6762

Website

tornadobus.com

Bus from Taqueria Guadalajara - Greenville to Charlotte

Average Duration

2h 28m

Estimated price

$19-55

Plane Show flights

Website

aa.com

Plane from Charlotte Airport (CLT) to Knoxville Airport (TYS)

Average Duration

1h 9m

Estimated price

$370-1400

Greenville to Knoxville: Overview of Bus, Train, Flight, and Car Trips

Traveling between Greenville and Knoxville offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.

🚗 Embark on a scenic road trip from Greenville to Knoxville covering a distance of 169 miles. Enjoy the picturesque journey through the heart of the Appalachian Mountains. 💲 Indulge in affordable travel options with car prices ranging from $30 to $45 for a one-way trip from Greenville to Knoxville. Explore budget-friendly ways to make the most of your adventure. 🛣️ Experience the Southern charm and hospitality as you drive for approximately 3 hours and 8 minutes to reach Knoxville. Immerse yourself in the rich culture and history of this vibrant Tennessee city.

Average price

$30 - $45

🚆 Embark on a scenic train journey from Greenville to Knoxville covering a distance of 412 miles. The route includes a transfer, adding an element of adventure to the trip. 🛤️ The first leg of the journey involves a bus ride towards Atlanta Bus Station, operated by FlixBus, with a travel time of approximately 2 hours and 45 minutes. From Atlanta, another bus will take you towards Flint Auburn Hill Bus Stop, with a duration of about 5 hours. 🎟️ With a total travel time of 11 hours and 48 minutes, this multi-step train adventure offers a unique way to explore the beautiful landscapes between Greenville and Knoxville, allowing you to sit back, relax, and enjoy the ride.

🛫 Flying from Greenville to Knoxville is a convenient and quick journey. The fastest option is a direct flight from Charlotte Airport to Knoxville Airport, which takes just 1 hour and 1 minute.

Departure Point

Charlotte Airport

Arrival Point

Knoxville Airport

🚌 Embark on a scenic bus journey from Greenville to Knoxville covering a distance of 419 miles in approximately 11 hours and 57 minutes with a transfer along the way. 🗺️ The first leg of the trip involves boarding a FlixBus from Greenville to Atlanta Bus Station, a 2-hour 45-minute ride. The next step includes a Greyhound bus journey from Atlanta to Knoxville, with a total travel time of around 5 hours.

Frequently asked questions

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The distance between Greenville and Knoxville is approximately 116 miles. The typical travel times vary depending on the mode of transportation. By car, the journey takes around 3 hours and 8 minutes. By bus, the travel time is significantly longer at approximately 18 hours and 47 minutes. Another option is to take a bus and then fly, which takes around 5 hours and 24 minutes.

The most cost-effective and time-efficient transportation option for traveling from Greenville to Knoxville is to drive. The distance between the two cities is approximately 116 miles, and the drive typically takes around 3 hours and 8 minutes. Driving not only offers the quickest travel time, but it also allows for greater flexibility in terms of departure and arrival times. Additionally, driving is often the cheapest option, with estimated costs ranging from $30 to $45 for fuel depending on the vehicle's fuel efficiency and gas prices.

To travel from Greenville to Knoxville without using public transportation, you can drive the distance of 169 miles. It takes approximately 3 hours and 8 minutes to drive from Greenville to Knoxville. The cost of the journey by car varies between $30 and $45, depending on factors such as gas prices and tolls.

The best way to travel from Greenville to Knoxville without a car is by bus. The journey takes approximately 18 hours and 47 minutes. The cost of the bus ticket may vary.

The flight between Greenville and Knoxville typically takes approximately 58 minutes with a direct flight from Charlotte Airport to Knoxville Airport. The cost of the flight can vary depending on factors such as the airline, time of booking, and availability of deals or discounts. It is advisable to check prices with different airlines and travel websites to get an accurate estimate of the cost of the flight.

There are plenty of accommodation options near Knoxville. A quick search shows that there are over 196 hotels available in the area. Prices for these hotels start at around $44 per night. With such a wide variety of options, you are sure to find a suitable place to stay that fits your budget and preferences.