
Greenville, SC, USA to Pittsburgh, PA, USA from $61: 6 ways by bus, train, flight or car
Compare Travel Options and Prices
How to Get from Greenville to Pittsburgh: Cheapest, Fastest and Best Way
1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.
Compare Train, Bus, Flight, and Driving Options
Get detailed, step-by-step directions below for your trip from Greenville to Pittsburgh with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

See more options
Traveling From Greenville to Pittsburgh
Traveling from Greenville to Pittsburgh offers you a fascinating contrast between Greenville's charming southern vibes and Pittsburgh's vibrant urban landscape rich in history and culture.
Best Neighbourhoods in Pittsburgh
Pittsburgh boasts diverse neighborhoods, each offering distinct experiences for visitors.
Best Times To Visit Pittsburgh's Attractions
To fully enjoy Pittsburgh's attractions, timing your visit can make all the difference.
Pittsburgh Weather: What to Expect Year-Round
Pittsburgh experiences a humid continental climate, with four distinct seasons influencing your travel plans throughout the year. Spring and fall provide mild temperatures and vibrant scenery, making them ideal times to explore the city, while winter snow can enhance the charm but may require additional layers for outdoor activities.
Dining Recommendation
Try the famous Primanti Brothers sandwich, where you’ll find hearty layers of meat, cheese, and fries all stuffed inside fresh bread, showcasing Pittsburgh’s unique take on comfort food. This bustling spot contrasts with the more traditional southern cuisine of Greenville, as it highlights bold flavors and an energetic atmosphere that captures the essence of the Steel City.
Greenville - Pittsburgh operators
Explore transport companies operating between Greenville and Pittsburgh, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Plane from Greenville/Spartanburg to Pittsburgh
Plane from Asheville to Pittsburgh
Plane from Greenville/Spartanburg to Pittsburgh via Charlotte
Plane from Greenville/Spartanburg to Pittsburgh via Philadelphia
Plane from Greenville/Spartanburg to Pittsburgh via New York La Guardia
Plane from Greenville/Spartanburg to Pittsburgh via Atlanta
Plane from Greenville/Spartanburg to Pittsburgh via New York La Guardia
Plane from Greenville/Spartanburg to Pittsburgh via Detroit
Plane from Asheville to Pittsburgh via Atlanta
Plane from Greenville/Spartanburg to Pittsburgh via Baltimore
Plane from Greenville/Spartanburg to Pittsburgh via Atlanta
Train from Charlotte Amtrak Station to Washington Union Station
Train from Washington Union Station to Pittsburgh Amtrak Station
Bus from Taqueria Guadalajara - Greenville to Charlotte
Bus from Charlotte, NC to Washington Union Station
Bus from Washington Union Station to Pittsburgh Intermodal Station
Other from Greenville to Asheville
Other from Greenville to Greenville/Spartanburg Airport
Greenville to Pittsburgh: Overview of Bus, Train, Flight, and Car Trips
Traveling between Greenville and Pittsburgh offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.
Frequently asked questions
Find out more about the route from Greenville to Pittsburgh.
Trips from Greenville
- Greenville to Winston-Salem
- Greenville to Orlando
- Greenville to Hilton Head Island
- Greenville to Washington
- Greenville to Sumter
- Greenville to Fayetteville
- Greenville to Chattanooga
- Greenville to Myrtle Beach
- Greenville to Nashville
- Greenville to Gastonia
- Greenville to Memphis
- Greenville to Tampa
- Greenville to Saluda
- Greenville to Columbia
- Greenville to Atlanta
- Greenville to Greensboro
- Greenville to Anderson
- Greenville to Miami
- Greenville to Hendersonville
- Greenville to Florence
- Greenville to Charleston
- Greenville to Summerville
- Greenville to Savannah
- Greenville to Richmond
- Greenville to Denver
- Greenville to Cancun
- Greenville to Charlotte
- Greenville to Asheville
- Greenville to Huntsville
- Greenville to Raleigh
- Greenville to Landrum
- Greenville to Dallas
- Greenville to Wilmington
- Greenville to Fort Lauderdale
- Greenville to Lexington
- Greenville to Greenwood
- Greenville to Spartanburg
- Greenville to Jacksonville
- Greenville to Knoxville
- Greenville to Clemson
Trips to Winston-Salem
- Cleveland to Pittsburgh
- Washington to Pittsburgh
- Baltimore to Pittsburgh
- Boston to Pittsburgh
- Newark to Pittsburgh
- Toronto to Pittsburgh
- Bedford to Pittsburgh
- Lancaster to Pittsburgh
- York to Pittsburgh
- Rochester to Pittsburgh
- Erie to Pittsburgh
- Charlotte to Pittsburgh
- Allentown to Pittsburgh
- New York City to Pittsburgh
- Philadelphia to Pittsburgh
- Scranton to Pittsburgh
- Chicago to Pittsburgh
- Harrisburg to Pittsburgh
- Cincinnati to Pittsburgh
- Nashville to Pittsburgh
- Indianapolis to Pittsburgh
- Altoona to Pittsburgh
- Columbus to Pittsburgh
- Johnstown to Pittsburgh
- State College to Pittsburgh
- Greensburg to Pittsburgh
- Syracuse to Pittsburgh
- Morgantown to Pittsburgh
- Tampa to Pittsburgh
- Dallas to Pittsburgh
- Orlando to Pittsburgh
- Houston to Pittsburgh
- Jacksonville to Pittsburgh
- Seattle to Pittsburgh
- Newark to Pittsburgh
- Denver to Pittsburgh
- Washington to Pittsburgh
- Newark to Pittsburgh
- Akron to Pittsburgh
- Morgantown to Pittsburgh