North Myrtle Beach, SC, USA to Key West, FL, USA from $117: 1 ways by bus, train, flight or car

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Get detailed, step-by-step directions below for your trip from North Myrtle Beach to Key West with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

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12h 

Estimated price

$117-117

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Duration: 12h

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Traveling From North Myrtle Beach to Key West

Traveling from North Myrtle Beach to Key West offers a striking contrast, with North Myrtle Beach's relaxed coastal charm giving way to Key West's vibrant island nightlife and rich cultural flair.

Best Neighbourhoods in Key West

Key West boasts diverse neighborhoods, each offering its own charm and vibe.

Old Town

• Known for its historic architecture.

• Vibrant nightlife with countless bars and restaurants.

Uptown

• Quieter atmosphere with local boutiques.

• Close to parks and community events.

New Town

• Family-friendly with spacious parks.

• Offers shopping and modern amenities.

Best Times To Visit Key West's Attractions

Timing your visits can greatly enhance your Key West experience.

Duval Street

Visit early morning or late afternoon to avoid peak crowds.

Ernest Hemingway Home and Museum

Midweek mornings are quieter for a more peaceful exploration.

Mallory Square

Arrive at least an hour before sunset for a good spot.

Key West Weather: What to Expect Year-Round

Key West enjoys a tropical climate, with warm temperatures and high humidity throughout the year; however, the best times to visit are typically from November to April when the weather is more comfortable. Consider how the weather impacts your travel experience, as summer months bring increased rain and storms, while winter offers the sunniest skies.

Dining Recommendation in Key West

When in Key West, you can't miss trying the conch fritters at Blue Heaven, where the lively outdoor setting and laid-back vibe create a dynamic experience that contrasts the more casual dining of North Myrtle Beach. The bold flavors of the local seafood and fresh island ingredients showcase the unique culinary identity of this vibrant destination.