
Knoxville, TN, USA to San Diego, CA, USA from $1883: 7 ways by bus, train, flight or car
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How to Get from Knoxville to San Diego: Cheapest, Fastest and Best Way
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Compare Train, Bus, Flight, and Driving Options
Get detailed, step-by-step directions below for your trip from Knoxville to San Diego with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

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Traveling From Knoxville to San Diego
The journey from Knoxville to San Diego offers a striking contrast between the lush Appalachian backdrop and the vibrant coastal cityscape, showcasing diverse landscapes and cultural experiences along the way.
Best Neighborhoods in San Diego
San Diego boasts diverse neighborhoods, each offering distinct experiences and attractions.
Best Times To Visit San Diego's Attractions
Making the most of your San Diego visit involves timing your trips to major attractions.
San Diego Weather: What to Expect Year-Round
San Diego features a mild climate with sunny skies most of the year, making it an inviting destination for outdoor activities. The best times to visit are spring and fall, as pleasant temperatures enhance your experience, while summer can bring larger crowds to popular spots.
Dining Recommendation
Try the fish tacos from Point Loma Seafoods, where fresh, local catches meet vibrant toppings and homemade sauces, offering a flavor that stands apart from the traditional Southern fare in Knoxville. The lively waterfront atmosphere adds to the experience, allowing you to savor each bite with an ocean breeze.
Knoxville - San Diego operators
Explore transport companies operating between Knoxville and San Diego, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Plane from Knoxville (TYS) to San Diego (SAN)
Plane from Asheville (AVL) to San Diego (SAN)
Plane from Chattanooga (CHA) to San Diego (SAN)
Plane from Knoxville (TYS) to San Diego (SAN)
Plane from Asheville (AVL) to San Diego (SAN)
Plane from Chattanooga (CHA) to San Diego (SAN)
Plane from Knoxville (TYS) to San Diego (SAN)
Plane from Knoxville (TYS) to San Diego (SAN)
Plane from Asheville (AVL) to San Diego (SAN)
Plane from Chattanooga (CHA) to San Diego (SAN)
Train from Los Angeles to San Diego
Train from Charlotte Amtrak Station to New Orleans Union Passenger Terminal
Train from New Orleans Union Passenger Terminal to Los Angeles
Train from St. Louis to Los Angeles
Bus from Greeneville to Nashville Bus Station
Bus from Nashville Bus Station to Dallas Bus Station
Bus from Dallas Bus Station to Los Angeles Union Station
Bus from Nashville Bus Station to St Louis Bus Station
Bus from Dallas Bus Station to Los Angeles Union Station
Other from Hot Springs, NC to Black Bear Resort
Knoxville to San Diego: Overview of Bus, Train, Flight, and Car Trips
Traveling between Knoxville and San Diego offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.
Frequently asked questions
Find out more about the route from Knoxville to San Diego.
Trips from Knoxville
- Knoxville to Chicago
- Knoxville to Gatlinburg
- Knoxville to New Orleans
- Knoxville to Cookeville
- Knoxville to Crossville
- Knoxville to New York City
- Knoxville to Memphis
- Knoxville to Roanoke
- Knoxville to Huntsville
- Knoxville to Indianapolis
- Knoxville to Raleigh
- Knoxville to Cincinnati
- Knoxville to Orlando
- Knoxville to Jackson
- Knoxville to Sevierville
- Knoxville to Columbia
- Knoxville to Louisville
- Knoxville to Seattle
- Knoxville to Asheville
- Knoxville to Destin
- Knoxville to Phoenix
- Knoxville to Birmingham
- Knoxville to Myrtle Beach
- Knoxville to Pensacola
- Knoxville to Greenville
- Knoxville to Denver
- Knoxville to Boston
- Knoxville to Pigeon Forge
- Knoxville to Johnson City
- Knoxville to Lexington
- Knoxville to Detroit
- Knoxville to Fort Lauderdale
- Knoxville to Dallas
- Knoxville to Nashville
- Knoxville to Miami
- Knoxville to Charlotte
- Knoxville to Omaha
- Knoxville to Chattanooga
- Knoxville to North Myrtle Beach
- Knoxville to Lexington
Trips to Chicago
- Seattle to San Diego
- Santa Monica to San Diego
- Los Angeles to San Diego
- Santa Barbara to San Diego
- Newport Beach to San Diego
- Irvine to San Diego
- Pasadena to San Diego
- Anaheim to San Diego
- Mexico City to San Diego
- San Francisco to San Diego
- Long Beach to San Diego
- San Jose to San Diego
- Las Vegas to San Diego
- Fullerton to San Diego
- San Bernardino to San Diego
- Burbank to San Diego
- Phoenix to San Diego
- Riverside to San Diego
- Huntington Beach to San Diego
- Atlanta to San Diego
- Carlsbad to San Diego
- Salt Lake City to San Diego
- Minneapolis to San Diego
- Detroit to San Diego
- Santa Rosa to San Diego
- Miami to San Diego
- Tampa to San Diego
- Escondido to San Diego
- Tijuana to San Diego
- Oceanside to San Diego
- Temecula to San Diego
- San Clemente to San Diego
- Saint Louis to San Diego
- San Luis Obispo to San Diego
- Bakersfield to San Diego
- Santa Ana to San Diego
- Encinitas to San Diego
- Yuma to San Diego
- Oklahoma City to San Diego
- El Cajon to San Diego