
San Antonio, TX, USA to Des Moines, IA, USA from $88: 7 ways by bus, train, flight or car
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How to Get from San Antonio to Des Moines: Cheapest, Fastest and Best Way
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Get detailed, step-by-step directions below for your trip from San Antonio to Des Moines with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

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Traveling From San Antonio to Des Moines
Your journey from San Antonio to Des Moines presents a fascinating contrast, transitioning from the vibrant Texas culture and sunny landscapes to the charming Midwestern warmth and rich local traditions.
Best Neighbourhoods in Des Moines
Des Moines boasts several vibrant neighborhoods, each offering unique experiences for visitors.
Best Times To Visit Des Moines's Attractions
Knowing when to visit Des Moines's attractions can enhance your experience significantly.
Des Moines Weather: What to Expect Year-Round
Des Moines experiences a humid continental climate with hot summers and cold winters, making late spring and early fall the most enjoyable times to visit. Being mindful of seasonal weather ensures you experience the city’s outdoor attractions at their best.
Dining in Des Moines: A Culinary Contrast
In Des Moines, savor the local favorite, a tender pork tenderloin sandwich, which offers a delightful contrast to the bold Tex-Mex flavors of San Antonio. Enjoy the cozy, welcoming atmosphere of a farm-to-table restaurant, showcasing fresh, locally sourced ingredients that reflect the region's agricultural heritage.
San Antonio - Des Moines operators
Explore transport companies operating between San Antonio and Des Moines, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Plane from San Antonio (SAT) to Des Moines (DSM)
Plane from San Antonio (SAT) to Des Moines (DSM)
Plane from San Antonio (SAT) to Des Moines (DSM)
Plane from San Antonio (SAT) to Des Moines (DSM)
Train from San Antonio Amtrak Station to St. Louis
Train from St. Louis to Kansas City
Bus from San Antonio Bus Station to Austin Eastside Bus Plaza
Bus from San Antonio Bus Station to Dallas Bus Station
Bus from Omaha, Ne to Des Moines, Ia
Bus from San Antonio to Omaha
San Antonio to Des Moines: Overview of Bus, Train, Flight, and Car Trips
Traveling between San Antonio and Des Moines offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.
Frequently asked questions
Find out more about the route from San Antonio to Des Moines.
Trips from San Antonio
- San Antonio to Round Rock
- San Antonio to College Station
- San Antonio to San Marcos
- San Antonio to Uvalde
- San Antonio to Houston
- San Antonio to Corpus Christi
- San Antonio to South Padre Island
- San Antonio to New Braunfels
- San Antonio to Kerrville
- San Antonio to Fredericksburg
- San Antonio to Waco
- San Antonio to Dallas
- San Antonio to Galveston
- San Antonio to Odessa
- San Antonio to New Orleans
- San Antonio to Boerne
- San Antonio to Fort Worth
- San Antonio to New York City
- San Antonio to Abilene
- San Antonio to San Angelo
- San Antonio to Eagle Pass
- San Antonio to Mexico City
- San Antonio to Albuquerque
- San Antonio to Monterrey
- San Antonio to McAllen
- San Antonio to Brownsville
- San Antonio to Arlington
- San Antonio to Los Angeles
- San Antonio to Laredo
- San Antonio to Colorado Springs
- San Antonio to Lake Charles
- San Antonio to Seattle
- San Antonio to Lubbock
- San Antonio to Guadalajara
- San Antonio to Miami
- San Antonio to Boston
- San Antonio to Austin
- San Antonio to Katy
- San Antonio to Cancun
- San Antonio to London
Trips to Round Rock
- Chicago to Des Moines
- Newton to Des Moines
- Minneapolis to Des Moines
- Dubuque to Des Moines
- Pella to Des Moines
- Indianapolis to Des Moines
- Storm Lake to Des Moines
- Creston to Des Moines
- Davenport to Des Moines
- Oskaloosa to Des Moines
- Madison to Des Moines
- Peoria to Des Moines
- Milwaukee to Des Moines
- Detroit to Des Moines
- Lincoln to Des Moines
- Omaha to Des Moines
- Kearney to Des Moines
- Iowa City to Des Moines
- Boston to Des Moines
- Fargo to Des Moines
- Seattle to Des Moines
- Houston to Des Moines
- Boone to Des Moines
- Saint Louis to Des Moines
- Ames to Des Moines
- Mason City to Des Moines
- Perry to Des Moines
- Dallas to Des Moines
- Story City to Des Moines
- Moline to Des Moines
- Charles City to Des Moines
- Cedar Rapids to Des Moines
- Waterloo to Des Moines
- Greenfield to Des Moines
- Kansas City to Des Moines
- Burlington to Des Moines
- Denison to Des Moines
- Eagle Grove to Des Moines
- Lincoln to Des Moines
- Kansas City to Des Moines