
Madison, WI, USA to Des Moines, IA, USA from $50: 8 ways by bus, train, flight or car
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How to Get from Madison to Des Moines: Cheapest, Fastest and Best Way
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Get detailed, step-by-step directions below for your trip from Madison to Des Moines with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

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Traveling From Madison to Des Moines
The journey from Madison to Des Moines offers a fascinating contrast between the vibrant college town atmosphere of Madison and the welcoming Midwestern charm of Des Moines.
Best Neighbourhoods in Des Moines
Des Moines boasts diverse neighborhoods that cater to various interests and lifestyles.
Best Times To Visit Des Moines's Attractions
Discovering Des Moines is best enjoyed with strategic timing for each highlight.
Des Moines Weather: What to Expect Year-Round
Des Moines experiences a humid continental climate, with hot summers and cold winters that shape the travel experience. Spring and fall offer mild temperatures, making these seasons ideal for exploring the city's attractions without extreme weather impacting your plans.
Dining Recommendation in Des Moines
Try the famous hand-battered fried chicken at Thelma's Treats, where the homestyle cooking reflects the heart of Midwestern cuisine, distinct from Madison's focus on farm-to-table. This dining spot not only serves up comforting flavors but also boasts a welcoming atmosphere filled with local charm, making it a delightful contrast to the more eclectic culinary scene in Madison.
Madison - Des Moines operators
Explore transport companies operating between Madison and Des Moines, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Bus from Madison, WI-Lake St. to Mall of America - IKEA - Bloomington
Bus from Madison, WI-Lake St. to Milwaukee Intermodal
Bus from Mall of America - Bloomington, MN to Des Moines, IA
Bus from Albert Lea, MN to Des Moines, IA
Bus from Madison, WI-Lake St. to Chicago Union Station
Bus from Madison, WI-Lake St. to O'Hare International Terminal 2
Bus from Chicago, IL to Des Moines, IA
Train from Portage to St. Paul-Minneapolis
Plane from Madison Airport (MSN) to Des Moines Airport (DSM)
Plane from Madison Airport (MSN) to Des Moines Airport (DSM)
Plane from Madison Airport (MSN) to Des Moines Airport (DSM)
Madison to Des Moines: Overview of Bus, Train, Flight, and Car Trips
Traveling between Madison and Des Moines offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.
Frequently asked questions
Find out more about the route from Madison to Des Moines.
Trips from Madison
- Madison to Waukesha
- Madison to Dubuque
- Madison to Spring Green
- Madison to Racine
- Madison to Cedar Rapids
- Madison to Appleton
- Madison to Wisconsin Dells
- Madison to Wausau
- Madison to Green Bay
- Madison to Platteville
- Madison to Oshkosh
- Madison to Indianapolis
- Madison to Beloit
- Madison to Janesville
- Madison to Minneapolis
- Madison to Toronto
- Madison to Springfield
- Madison to New Orleans
- Madison to Seattle
- Madison to San Francisco
- Madison to Detroit
- Madison to Milwaukee
- Madison to Chicago
- Madison to Middleton
- Madison to Siesta Key
- Madison to San Diego
- Madison to Fort Myers
- Madison to Las Vegas
- Madison to La Crosse
- Madison to Rockford
- Madison to Tucson
- Madison to Pella
- Madison to Aurora
- Madison to Tampa
- Madison to Myrtle Beach
- Madison to Cleveland
- Madison to Deforest
- Madison to Miami
- Madison to Dallas
- Madison to Eau Claire
Trips to Waukesha
- Chicago to Des Moines
- Minneapolis to Des Moines
- Dubuque to Des Moines
- Pella to Des Moines
- Indianapolis to Des Moines
- Davenport to Des Moines
- Oskaloosa to Des Moines
- Peoria to Des Moines
- Milwaukee to Des Moines
- Detroit to Des Moines
- New York City to Des Moines
- Lincoln to Des Moines
- Omaha to Des Moines
- Kearney to Des Moines
- Iowa City to Des Moines
- San Antonio to Des Moines
- Boston to Des Moines
- Seattle to Des Moines
- Charleston to Des Moines
- Houston to Des Moines
- Boone to Des Moines
- Saint Louis to Des Moines
- Ames to Des Moines
- Harpers Ferry to Des Moines
- Mason City to Des Moines
- Perry to Des Moines
- Dallas to Des Moines
- Story City to Des Moines
- Moline to Des Moines
- Charles City to Des Moines
- Cedar Rapids to Des Moines
- Waterloo to Des Moines
- Greenfield to Des Moines
- Kansas City to Des Moines
- Atlantic to Des Moines
- Burlington to Des Moines
- Denison to Des Moines
- Eagle Grove to Des Moines
- Lincoln to Des Moines
- Kansas City to Des Moines