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Des Moines, IA, USA to Charleston, SC, USA from $131: 6 ways by bus, train, flight or car

Compare Travel Options and Prices

from
Des Moines, United States of America
to
Charleston, United States of America

How to Get from Des Moines to Charleston: Cheapest, Fastest and Best Way

1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.

$131 - Bus, TrainBest price
1565 kmDistance
6h 18m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Des Moines to Charleston with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

Company
Various
Plane
Average Duration
6h  18m
Estimated price
$189-523
Recommended
Company
Various
Bus
Train
Average Duration
37h  52m
Estimated price
$131-656
Cheapest
route map
Distance: 1565 km
Duration: 6h 18m

See more options

Company
Various
Bus
Average Duration
38h  36m
Estimated price
$210-1890
Company
Various
Drive
Average Duration
20h 
Estimated price
$210-1890
Company
Various
Plane
Drive
Average Duration
6h  26m
Estimated price
$264-695
Company
Various
Plane
Drive
Average Duration
7h  15m
Estimated price
$305-847
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Traveling From Des Moines to Charleston

Traveling from Des Moines to Charleston offers a striking contrast, as you transition from the Midwestern charm of rolling plains to the vibrant coastal atmosphere and rich history of the South.

Best Neighbourhoods in Charleston

Charleston features diverse neighborhoods, each with distinct charm and character.

Historic District
• Iconic cobblestone streets and antebellum architecture.
• Home to renowned restaurants and local shops.
West Ashley
• Family-friendly atmosphere with ample green spaces.
• Great dining options, including barbecue and seafood.
Folly Beach
• Laid-back vibe with stunning ocean views.
• Popular spot for water sports and beach relaxation.

Best Times To Visit Charleston's Attractions

Timing your visits can significantly enhance your Charleston experience.

The Battery
Visit early morning or late afternoon for fewer tourists and stunning light.
Magnolia Plantation and Gardens
Weekdays in spring offer beautiful blooms and a quieter atmosphere.
Rainbow Row
Early mornings reveal fewer crowds and the best photo opportunities.

Charleston Weather: What to Expect Year-Round

Charleston boasts a humid subtropical climate with warm summers and mild winters, making it an inviting destination year-round. The best times to visit are spring and fall, as pleasant temperatures enhance your outdoor adventures and sightseeing.

Dining Recommendation in Charleston

When in Charleston, you can't miss trying shrimp and grits at Husk, where locally sourced ingredients create a bold Southern flavor profile that contrasts with the heartier fare often found in Des Moines. The vibrant atmosphere, along with the emphasis on historic recipes and innovative twists, truly sets Charleston's dining scene apart.

Des Moines - Charleston operators

Explore transport companies operating between Des Moines and Charleston, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Plane Show flights
Website
aa.com

Plane from Des Moines (DSM) to Charleston (CHS)

Average Duration
6h 44m
Estimated price
$1895-1896

Plane from Des Moines (DSM) to Charlotte

Average Duration
5h 33m
Estimated price
$1895-1896

Plane from Des Moines (DSM) to Reagan Washington

Average Duration
5h 44m
Estimated price
$1891-1896
Website
delta.com

Plane from Des Moines (DSM) to Charleston (CHS)

Average Duration
5h 10m
Estimated price
$1895-5233

Plane from Des Moines (DSM) to Minneapolis

Average Duration
6h 46m
Estimated price
$5234-5233
Website
united.com

Plane from Des Moines (DSM) to Charleston (CHS)

Average Duration
5h 41m
Estimated price
$5234-1896
Website
southwest.com

Plane from Des Moines (DSM) to Charleston (CHS)

Average Duration
9h 55m
Estimated price
$5239-1892
Train Show train routes
Contact phone
+1 800-872-7245
Website
amtrak.com

Train from Galesburg Amtrak Station to Chicago Union Station

Average Duration
2h 56m
Estimated price
$1310-1311

Train from Chicago Union Station to Rockville Amtrak

Average Duration
16h 36m
Estimated price
$6563-5235

Train from Washington Union Station to Charleston Amtrak Station

Average Duration
9h 24m
Estimated price
$1313-1891
Bus Show bus routes
Contact phone
1(800) 992-4618
Website
burlingtontrailways.com

Bus from Des Moines, Ia to Burlington, Ia

Average Duration
Estimated price
$6560-13100

Bus from Burlington, Ia to Galesburg, Il

Average Duration
Estimated price
$6569-6560

Bus from Des Moines, Ia to Galesburg, Il

Average Duration
Estimated price
$1318-6566

Bus from Indianapolis, IN to New York

Average Duration
11h
Estimated price
$1893-1893
Contact phone
+1 212 965 8880
Website
starlinebus.com

Bus from New York to Charleston

Average Duration
12h 45m
Estimated price
$6568-3050

Des Moines to Charleston: Overview of Bus, Train, Flight, and Car Trips

Traveling between Des Moines and Charleston offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.

🚗 Embark on a scenic road trip from Des Moines to Charleston spanning 1207 miles, offering a blend of charming Midwest landscapes and coastal beauty. 💸 Enjoy a budget-friendly journey with car travel prices ranging from $210 to $320, giving you the flexibility to tailor the trip according to your preferences and comfort. 🌴 Arrive in Charleston after approximately 20 hours of driving, where you can feast on Southern cuisine, explore historic sites, and unwind on the beautiful beaches, making your road trip an unforgettable adventure.
Average price
$210 - $320
🚆 Start your journey from Des Moines by taking a bus to Kansas City with Jefferson Lines, then transfer to a bus to St. Louis with Greyhound. Enjoy the scenic views as you travel towards your destination. 🛤️ Next, board a bus to Nashville, followed by a bus to Atlanta, experiencing the diversity of landscapes along the way. Arrive at Columbia before heading towards your final stop, Charleston. 🌴 Finally, complete your train trip with a short bus ride to Mary St / Meeting St in Charleston, using the Charleston Area Regional Transportation Authority. Unwind and enjoy the charm of Charleston after your long but rewarding journey.
🛫 Traveling from Des Moines to Charleston by plane involves a connecting flight due to the lack of direct flights between the two cities. The quickest route typically includes one stopover and lasts approximately 4 hours and 44 minutes. 💸 The cost of a flight between Charleston and Des Moines can vary, ranging from $189 to $523. While prices fluctuate based on factors such as airline, booking time, and demand, travelers have the opportunity to compare fares and select a ticket that fits their budget for a journey of approximately 6 hours and 18 minutes.
Departure Point
Des Moines Airport
Arrival Point
Charleston Airport. The quickest flight takes 4h 44m and has one stopover
🛤️ The route typically takes about 38.5 hours to cover the 1,592-mile distance, including transfers in cities like Galesburg, Indianapolis, New York, and Columbia.
Departure Point
Des Moines, Ia station
Arrival Point
Charleston station

Frequently asked questions

Find out more about the route from Des Moines to Charleston.

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The distance between Des Moines and Charleston is 972 miles, or 1207.3 miles by road. Depending on the mode of transportation, the travel times vary. It takes approximately 36 hours and 51 minutes to reach Charleston from Des Moines by taking a night bus and then a train. Alternatively, one can fly from Des Moines to Charleston in about 4 hours and 46 minutes. Driving by car takes around 20 hours, while traveling by bus takes approximately 38 hours and 43 minutes.
The most cost-effective transportation option for traveling from Des Moines to Charleston is taking a night bus and then a train. This option ranges in price from $120 to $600 and takes approximately 36 hours and 51 minutes. However, if time is more important, the quickest way to reach Charleston is by flying. This option typically costs between $210 and $600 and takes around 4 hours and 46 minutes.
To travel from Des Moines to Charleston without using public transportation, the best option is to drive. The road distance is approximately 1207 miles, and the drive takes around 20 hours. It is recommended to budget between $210 and $320 for fuel and potential tolls, depending on the car's fuel efficiency and current gas prices.
If you want to travel from Des Moines to Charleston without a car, the best option is to take a night bus and a train. This journey takes approximately 36 hours and 51 minutes. The cost of this type of transportation typically ranges between $120 and $600. It is a long journey but can be a cost-effective option for those who prefer not to drive.
Yes, there is a indirect link between Des Moines and Charleston. There is no direct bus service, but there are options available with transfers. The journey includes departures from Des Moines and transfers in Galesburg Amtrak, Ctc-R, Indianapolis, IN, and New York. The total travel time is approximately 38 hours and 43 minutes. The bus services are operated by Burlington Trailways and Atlanta Tours Inc.
The flight between Des Moines and Charleston typically takes around 4 hours and 21 minutes with one stopover. However, there is no direct flight available, so passengers will need to make a connecting flight. The cost of the flight can range from $212 to $585, depending on factors such as the airline, time of booking, and availability of deals or discounts.
There are plenty of accommodation options near Charleston with over 913 hotels to choose from. Prices for these hotels start at $61 per night. Whether you're looking for luxury resorts, budget-friendly options, or cozy bed and breakfasts, you will have no trouble finding somewhere to stay in Charleston. It is recommended to book in advance to secure the best deals and availability during your desired travel dates.

Trips from Des Moines

Trips to Charleston