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Saint Louis, MO, USA to La Crosse, WI, USA from $23: 5 ways by bus, train, flight or car

Compare Travel Options and Prices

from
Saint Louis, United States of America
to
La Crosse, United States of America

How to Get from Saint Louis to La Crosse: Cheapest, Fastest and Best Way

1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.

$23 by trainBest price
586 kmDistance
5h 31m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Saint Louis to La Crosse with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

Company
Various
Plane
Average Duration
5h  31m
Estimated price
$254-878
Recommended
Company
Amtrak
Train
Average Duration
11h  24m
Estimated price
$23-251
Cheapest
route map
Distance: 586 km
Duration: 5h 31m

See more options

Company
Greyhound USA
Bus
Average Duration
14h  13m
Estimated price
$88-198
Company
Various
Bus
Bus
Average Duration
15h  20m
Estimated price
$88-198
Company
Various
Drive
Average Duration
8h  6m
Estimated price
$90-130

Traveling From Saint Louis to La Crosse

The journey from Saint Louis to La Crosse offers a fascinating contrast between the bustling urban energy of the Gateway City and the serene natural beauty nestled along the Mississippi River in La Crosse.

Best Neighbourhoods in La Crosse

La Crosse boasts vibrant neighborhoods, each offering distinct experiences.

Downtown La Crosse
• Rich dining and nightlife options.
• Historic architecture and beautiful river views.
Grandad Bluff
• Stunning panoramic views of the city.
• Great hiking trails and picnic areas.
Northside
• Quieter, residential feel with parks.
• Access to local shops and community events.

Best Times To Visit La Crosse's Attractions

Timing your visits can truly elevate your La Crosse experience.

Riverside Park
Visit early mornings on weekdays for peaceful walks and fewer crowds.
Grandad Bluff
Try late afternoons during weekdays for stunning sunset views.
La Crosse Queen Cruises
Opt for early season cruises in spring to enjoy a relaxed atmosphere.

La Crosse Weather: What to Expect Year-Round

La Crosse experiences a humid continental climate, featuring hot summers and cold winters, which can significantly influence your travel plans. Visiting during late spring or early fall offers moderate temperatures and pleasant conditions for exploring the area.

Dining Recommendation in La Crosse

Try the fresh fish tacos at The Waterfront Restaurant, which highlight local catch and pair beautifully with a vibrant, riverfront atmosphere. This experience contrasts with the barbecue-rich cuisine of Saint Louis, showcasing a lighter, more coastal flavor profile that reflects the unique spirit of the area.

Saint Louis - La Crosse operators

Explore transport companies operating between Saint Louis and La Crosse, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Plane
Website
aa.com

Plane from St. Louis (STL) to La Crosse (LSE)

Average Duration
5h 31m
Estimated price
$254-878
Train
Contact phone
+1 800-872-7245
Website
amtrak.com

Train from St. Louis to Chicago Union Station

Average Duration
5h 25m
Estimated price
$22-2540

Train from Chicago Union Station to La Crosse

Average Duration
4h 59m
Estimated price
$23-130
Bus
Contact phone
+1 214-849-8100
Website
greyhound.com

Bus from St. Louis Bus Station to Chicago Bus Station

Average Duration
6h 39m
Estimated price
$88-198

Bus from Chicago Union Station to Madison

Average Duration
3h 35m
Estimated price
$0-0

Bus from Madison, WI-Lake St. to La Crosse, WI

Average Duration
3h 25m
Estimated price
$0-0
all-pages.other Show other routes
Contact phone
+1 608-752-5407
Website
https://www.coachusa.com/van-galder-bus-company

Other from Chicago Union Station to Madison, WI-Lake St.

Average Duration
3h 40m
Estimated price
$23-85
Contact phone
+1-858-800-8898
Website
jeffersonlines.com

Other from Madison, WI-Lake St. to La Crosse, WI

Average Duration
Estimated price
$0-0

Frequently asked questions

Find out more about the route from Saint Louis to La Crosse.

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The distance between Saint Louis and La Crosse is approximately 364 miles. If you choose to drive, it will take you around 8 hours and 6 minutes to reach your destination. Taking a train is also an option, with a travel time of about 11 hours and 24 minutes. For a quicker option, you can consider flying, which typically takes around 6 hours and 7 minutes. Taking a bus is the longest option, with a travel time of approximately 14 hours and 14 minutes.
The most cost-effective option for traveling from Saint Louis to La Crosse is by train, with prices ranging from $22 to $260. Although the train journey takes 11 hours and 24 minutes, it is the cheaper option for budget-conscious travelers. However, if time is a factor, the quickest way to travel between the two cities is by plane, with a travel time of 6 hours and 7 minutes, but at a higher cost of $260 to $900. It ultimately depends on the traveler's priorities and budget constraints.
The train ticket prices for travel between Saint Louis and La Crosse range from $23 to $251, depending on the class and availability. The bus ticket prices for travel from La Crosse to Saint Louis range from $88 to $198, depending on the type of bus and fare options. It is recommended to book in advance to secure the best prices and availability for your preferred mode of transportation.
To get from Saint Louis to La Crosse without using public transportation, the best option is to drive. The distance between the two cities is 497 miles, and it takes around 8 hours and 6 minutes to drive. The prices for renting a car vary between $90 and $130, depending on the rental company and the type of car chosen. Driving allows you the flexibility to stop at different attractions along the way and explore the scenic routes.
To travel from St. Louis to La Crosse without a car, the best option is to take a train. The train journey takes approximately 11 hours and 24 minutes and costs between $22 and $260. Another option is to fly, which takes around 6 hours and 7 minutes, with ticket prices ranging from $260 to $900. If you prefer a longer but more affordable option, you can take a bus, which takes about 14 hours and 14 minutes and costs between $85 and $200.
There is no direct train or bus link between Saint Louis and La Crosse. However, there are train services operated by Amtrak that depart from St. Louis and arrive at La Crosse with a transfer in Chicago Union Station, taking approximately 11 hours and 24 minutes. Similarly, there are bus services operated by Greyhound USA and Jefferson Lines that depart from St. Louis Bus Station and arrive at La Crosse with transfers in Chicago Union Station and Madison taking approximately 14 hours and 14 minutes.
The flight duration between Saint Louis and La Crosse varies depending on the number of layovers, with the quickest option taking approximately 4 hours and 51 minutes. However, there are no direct flights between the two cities, so passengers would typically have to make a stopover. The cost of a flight between La Crosse and Saint Louis can range from $264 to $878, depending on factors such as airline, time of booking, and availability.
There are plenty of accommodation options available near La Crosse. With over 37 hotels to choose from, travelers can find something suitable for their needs and budget. Prices start at a low rate of $41, offering a range of affordable options. Whether you are looking for a luxury hotel or a budget-friendly stay, you can easily find a place to stay near La Crosse.

Trips from Saint Louis