
Sioux Falls, SD, USA to La Crosse, WI, USA from $43: 8 ways by bus, train, flight or car
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How to Get from Sioux Falls to La Crosse: Cheapest, Fastest and Best Way
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Get detailed, step-by-step directions below for your trip from Sioux Falls to La Crosse with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

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Traveling From Sioux Falls to La Crosse
Your journey from Sioux Falls to La Crosse offers a fascinating blend of South Dakota's urban charm and Wisconsin's scenic riverfront allure.
Best Neighbourhoods in La Crosse
La Crosse’s neighborhoods offer diverse experiences that cater to all tastes.
Best Times To Visit La Crosse's Attractions
Timing your visit to La Crosse can enhance your experience at various attractions.
La Crosse Weather: What to Expect Year-Round
La Crosse experiences a mix of warm summers and cold winters, making each season unique for travelers. Planning your visit around spring or early fall offers mild weather, ideal for exploring the area without extreme heat or snow.
Dining Recommendation in La Crosse
Head to The Waterfront Restaurant, where you can savor their signature walleye, a dish that captures the essence of Wisconsin's fresh local fish. This experience contrasts with Sioux Falls' more meat-centric offerings, allowing you to enjoy a laid-back riverside atmosphere paired with vibrant flavors and locally sourced ingredients.
Sioux Falls - La Crosse operators
Explore transport companies operating between Sioux Falls and La Crosse, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Plane from Sioux Falls (FSD) to La Crosse (LSE)
Plane from Sioux Falls (FSD) to Rochester (RST) via Chicago O'Hare
Plane from Sioux Falls (FSD) to La Crosse (LSE)
Plane from Sioux Falls (FSD) to Minneapolis (MSP)
Train from St. Paul-Minneapolis to La Crosse
Bus from Sioux Falls, SD to Burnsville, MN
Bus from Sioux Falls, SD to Minneapolis Bus Depot
Bus from Sioux Falls, SD to Albert Lea, MN
Bus from Sioux Falls, SD to Burnsville, MN
Bus from Minneapolis-St. Paul International Airport, MN to La Crosse, WI
Sioux Falls to La Crosse: Overview of Bus, Train, Flight, and Car Trips
Traveling between Sioux Falls and La Crosse offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.
Frequently asked questions
Find out more about the route from Sioux Falls to La Crosse.
Trips from Sioux Falls
- Sioux Falls to Okoboji
- Sioux Falls to Chamberlain
- Sioux Falls to Chicago
- Sioux Falls to Worthington
- Sioux Falls to Des Moines
- Sioux Falls to Windom
- Sioux Falls to Vermillion
- Sioux Falls to Watertown
- Sioux Falls to Huron
- Sioux Falls to Pipestone
- Sioux Falls to Norfolk
- Sioux Falls to Pierre
- Sioux Falls to Rapid City
- Sioux Falls to Deadwood
- Sioux Falls to Sturgis
- Sioux Falls to Salt Lake City
- Sioux Falls to Rochester
- Sioux Falls to Aberdeen
- Sioux Falls to Fargo
- Sioux Falls to Indianapolis
- Sioux Falls to Nashville
- Sioux Falls to Brookings
- Sioux Falls to Duluth
- Sioux Falls to Orlando
- Sioux Falls to Las Vegas
- Sioux Falls to Gillette
- Sioux Falls to Badlands National Park
- Sioux Falls to Dell Rapids
- Sioux Falls to Denver
- Sioux Falls to Minneapolis
- Sioux Falls to Bismarck
- Sioux Falls to Billings
- Sioux Falls to San Diego
- Sioux Falls to Mitchell
- Sioux Falls to Sioux City
- Sioux Falls to Yankton
- Sioux Falls to Omaha
- Sioux Falls to Kansas City
- Sioux Falls to Des Moines
- Sioux Falls to Kansas City
Trips to Okoboji
- Winona to La Crosse
- Milwaukee to La Crosse
- Chicago to La Crosse
- Eau Claire to La Crosse
- Tomah to La Crosse
- Minneapolis to La Crosse
- Kenosha to La Crosse
- Green Bay to La Crosse
- Albert Lea to La Crosse
- Stevens Point to La Crosse
- Madison to La Crosse
- Des Moines to La Crosse
- Cedar Rapids to La Crosse
- Denver to La Crosse
- Saint Louis to La Crosse
- Chippewa Falls to La Crosse
- Appleton to La Crosse
- Rochester to La Crosse
- Dallas to La Crosse
- Saint Paul to La Crosse
- Wisconsin Dells to La Crosse
- Mankato to La Crosse
- Fort Dodge to La Crosse
- Austin to La Crosse