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Tupelo, MS, USA to Knoxville, TN, USA from $142: 6 ways by bus, train, flight or car

Compare Travel Options and Prices

from
Tupelo, United States of America
to
Knoxville, United States of America

How to Get from Tupelo to Knoxville: Cheapest, Fastest and Best Way

1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.

$142 by busBest price
478 kmDistance
5h 5m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Tupelo to Knoxville with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

Company
various
Drive
Plane
Average Duration
5h  5m
Estimated price
$196-586
Recommended
Company
various
Bus
Bus
Drive
Average Duration
15h  6m
Estimated price
$142-285
Cheapest
route map
Distance: 478 km
Duration: 5h 5m

See more options

Company
various
Bus
Average Duration
41h  31m
Estimated price
$188-1960
Company
various
Bus
Plane
Average Duration
7h  35m
Estimated price
$206-576
Company
various
Drive
Plane
Average Duration
5h  42m
Estimated price
$289-555
Company
various
Drive
Average Duration
6h  27m
Estimated price
$1961-1962

Traveling From Tupelo to Knoxville

The journey from Tupelo to Knoxville offers a blend of Tupelo's small-town charm and rich musical heritage with Knoxville's vibrant arts scene and stunning Smoky Mountain views.

Best Neighborhoods in Knoxville

Knoxville features diverse neighborhoods, each with its own character and charm.

Old City
• Vibrant nightlife with popular bars and music venues.
• Unique shops and galleries showcasing local art.
West Knoxville
• Family-friendly with plenty of parks and recreational options.
• Great dining and shopping at Turkey Creek.
Downtown Knoxville
• Historic architecture blended with modern amenities.
• Home to numerous festivals and cultural events.

Best Times To Visit Knoxville's Attractions

Timing your visits can significantly enhance your experience in Knoxville.

Ijams Nature Center
Weekdays early in the morning offer tranquility and fewer visitors.
Knoxville Museum of Art
Visit during the first Friday of each month for free entry and events.
Tennessee Theatre
Attending weekday matinees often results in smaller crowds and better seating.

Knoxville Weather: What to Expect Year-Round

Knoxville experiences a humid subtropical climate, with hot summers and mild winters, making spring and fall the most comfortable times to visit. Being aware of the weather can enhance your travel experience, as it influences outdoor activities and event schedules.

Dining Recommendation in Knoxville

Try the smoked brisket at Sweet P's BBQ, where you'll find a bold blend of flavors that contrasts with Tupelo's Southern comfort food staples. The lively atmosphere and emphasis on locally sourced ingredients create a distinctive culinary experience that truly showcases Knoxville's vibrant food scene.

Tupelo - Knoxville operators

Explore transport companies operating between Tupelo and Knoxville, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Bus Show bus routes
Contact phone
+1 214-849-8100
Website
https://www.greyhound.com/

Bus from Tupelo to Memphis Bus Station

Average Duration
1h 50m
Estimated price
$1422-1423

Bus from Tupelo to Atlanta Bus Station

Average Duration
6h
Estimated price
$1424-1425

Bus from Memphis Bus Station to Nashville Bus Station

Average Duration
3h 45m
Estimated price
$1426-1427

Bus from Nashville Bus Station to Greeneville

Average Duration
4h 40m
Estimated price
$1428-1961
Contact phone
+1 (855) 626-8585
Website
https://www.flixbus.com/

Bus from Atlanta Bus Station to New York City Chinatown

Average Duration
18h
Estimated price
$1961-1429
Contact phone
646-630-7186
Website
https://www.wandacoach.com/

Bus from New York, NY to Knoxville

Average Duration
11h 45m
Estimated price
$2850-5866
Contact phone
+1 615-939-8887
Website
http://nytnbus.com/

Bus from New York City to Knoxville

Average Duration
12h
Estimated price
$2851-2852
Plane Show flights
Website
https://www.delta.com/

Plane from Golden Triangle Regional to Knoxville

Average Duration
5h 49m
Estimated price
$5866-5865

Plane from Huntsville to Knoxville

Average Duration
3h 15m
Estimated price
$5867-5868

Plane from Memphis to Knoxville

Average Duration
3h 55m
Estimated price
$1965-5868
Website
http://aa.com/

Plane from Huntsville to Knoxville

Average Duration
4h 49m
Estimated price
$1968-1969
Website
http://united.com/

Plane from Huntsville to Knoxville

Average Duration
5h 22m
Estimated price
$5869-5861

Plane from Memphis to Knoxville

Average Duration
4h 36m
Estimated price
$5864-5868

Tupelo to Knoxville: Overview of Bus, Train, Flight, and Car Trips

Traveling between Tupelo and Knoxville offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.

🚗 Embark on a scenic road trip from Tupelo to Knoxville spanning 391 miles of beautiful countryside. Enjoy the journey through charming towns and picturesque landscapes along the way. ⛽️ The approximate 6-hour and 27-minute drive offers a mix of highways and backroads, providing a glimpse into the heart of the southern United States. With prices ranging from $70 to $110 for the trip, fuel up and hit the road for an unforgettable adventure.
Average price
$70 - $110
🛫 Starting your journey from Tupelo you'll need to take a connecting flight to reach Knoxville as there are no direct flights from Golden Triangle Regional Airport. The quickest option with one stopover typically takes around 3 hours and 29 minutes.
Departure Point
Golden Triangle Regional Airport
Arrival Point
Knoxville Airport. The quickest flight takes 3h 29m and has one stopover
🚌 Embark on a scenic bus journey from Tupelo to Knoxville taking approximately 41 hours and 31 minutes to reach your destination. Sit back, relax, and enjoy the ride through the beautiful landscapes of the southeastern United States. 💰 Prices for bus tickets between Knoxville and Tupelo can range from $188 to $435, offering budget-friendly options for travelers looking to explore these charming cities without breaking the bank. Compare different fares and schedules to choose the best option that suits your travel preferences and budget.

Frequently asked questions

Find out more about the route from Tupelo to Knoxville.

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The distance between Tupelo and Knoxville is approximately 297 miles. By car, it takes around 6 hours and 27 minutes to travel from Tupelo to Knoxville. If you prefer to fly, you can reach Knoxville from Tupelo by driving to Golden Triangle Regional Airport and then taking a flight, which typically takes about 6 hours and 5 minutes. Alternatively, if you choose to take a bus, the travel time can be longer, averaging around 11 hours and 38 minutes.
The most cost-effective and time-efficient transportation option for traveling from Tupelo to Knoxville is to drive and fly. This option takes approximately 6 hours and 5 minutes, and the cost ranges from $170 to $600. Alternatively, driving alone is also a cost-effective option, taking about 6 hours and 27 minutes at a cost of $70 to $110. Taking a bus is the least time-efficient option, with a travel time of 11 hours and 38 minutes.
The prices of a bus ticket between Knoxville and Tupelo vary from $149 to $252. The exact price depends on factors such as the time and date of travel, as well as the bus company chosen. It is recommended to check with different bus operators or online travel platforms to find the best deal for your specific travel dates.
To travel from Tupelo to Knoxville without using public transportation, you can drive the distance of 391 miles. The journey typically takes around 6 hours and 27 minutes by car. The cost of fuel for this trip can range from $70 to $110, depending on the vehicle's fuel efficiency and current gas prices.
If you want to travel from Tupelo to Knoxville without a car, the best option is to take a bus. The journey by bus takes approximately 11 hours and 38 minutes. The cost of the bus ticket can range from $140 to $260. This is a convenient and affordable way to reach Knoxville from Tupelo if you do not have access to a car.
The flight duration between Tupelo and Knoxville varies depending on the number of stopovers. The quickest route available takes approximately 4 hours and 29 minutes with one stopover. However, it's important to note that there are no direct flights available from Golden Triangle Regional Airport to Knoxville Airport. The cost of the flight can vary depending on factors such as the time of booking, airline, and class of service. It is recommended to check with airlines or travel websites for the most up-to-date pricing information.
There are plenty of accommodation options near Knoxville. With 196+ hotels available, you will have a wide range to choose from. Prices start at $44, making it possible to find something suitable for every budget. Whether you are looking for a luxury hotel, a budget-friendly option, or something in between, you are sure to find a place to stay that meets your needs.

Trips to Knoxville