Durham, NC, USA to Knoxville, TN, USA from $132: 6 ways by bus, train, flight or car

Compare Travel Options and Prices

How to Get from Durham to Knoxville: Cheapest, Fastest and Best Way

1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.

$132 by busBest price

454 kmDistance

5h 40m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Durham to Knoxville with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

See more options

Sort by

Browse car rentals Explore flights

Traveling From Durham to Knoxville

Traveling from Durham to Knoxville offers a striking contrast between Durham's vibrant cultural scene and Knoxville's charming southern hospitality.

Best Neighbourhoods in Knoxville

Knoxville boasts diverse neighborhoods, each offering a distinctive experience.

Old City

• Lively nightlife with unique bars and restaurants.

• Rich history with vintage architecture and art galleries.

Market Square

• Central hub for shopping and dining options.

• Frequent events and farmers' markets throughout the year.

Fort Sanders

• Close to the University of Tennessee's vibrant atmosphere.

• Charming streets with historic homes and local coffee shops.

Best Times To Visit Knoxville's Attractions

Timing your visit can greatly enhance your experience in Knoxville.

Knoxville Zoo

Visit in the morning during weekdays for fewer crowds and active animals.

World's Fair Park

Spring and fall offer pleasant weather and blooming gardens with fewer visitors.

Ijams Nature Center

Go on weekdays early in the morning to enjoy serene trails and natural beauty.

Knoxville Weather: What to Expect Year-Round

Knoxville enjoys a humid subtropical climate, characterized by hot summers and mild winters, making spring and fall the best times to visit for comfortable temperatures. Be mindful of seasonal weather patterns, as they can influence outdoor activities and travel plans.

Dining Recommendation in Knoxville

In Knoxville, don’t miss the chance to try a plate of smoked brisket from The Tennessee BBQ Joint, an experience that showcases bold, rich flavors that contrast sharply with Durham's more diverse culinary scene. The relaxed atmosphere and emphasis on local ingredients create a dining experience that truly celebrates southern barbecue culture.

Durham - Knoxville operators

Explore transport companies operating between Durham and Knoxville, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Train

Contact phone

+1 800-872-7245

Website

https://www.amtrak.com/home.html

Train from Durham Amtrak Station to Charlotte Amtrak Station

Average Duration

2h 38m

Estimated price

$1320-90

Bus

Contact phone

+1 877-462-6342

Website

https://us.megabus.com

Bus from Durham, NC to Charlotte, NC

Average Duration

2h 45m

Estimated price

$7135-1327

Contact phone

+1 214-849-8100

Website

https://www.greyhound.com/

Bus from Durham to Greensboro Bus Stop

Average Duration

Estimated price

$7136-1328

Contact phone

+1 (855) 626-8585

Website

https://www.flixbus.com

Bus from Durham to Greensboro Bus Stop

Average Duration

55m

Estimated price

$7137-1327

Contact phone

+1 828-327-2340

Website

http://hickoryhop.com

Bus from Charlotte Airport to Blowing Rock - Tanger Outlets

Average Duration

Estimated price

$7131-90

Bus from Charlotte Airport to Willie Brooks BBQ - Boone

Average Duration

2h 15m

Estimated price

$7131-7130

Taxi

Contact phone

+1 828-719-8477

Website

https://facebook.com/

Taxi from Blowing Rock - Tanger Outlets to Black Bear Resort

Average Duration

1h 21m

Estimated price

$140-7138

Shuttle

Contact phone

+1-423-725-5988

Website

http://blackbearresorttn.com

Shuttle from Black Bear Resort to Hot Springs, NC

Average Duration

1h 15m

Estimated price

$7133-0

Shuttle from Boone to Black Bear Resort

Average Duration

Estimated price

$7134-0

Plane Show flights

Website

https://www.delta.com

Plane from Raleigh/Durham (RDU) to Knoxville (TYS)

Average Duration

5h 9m

Estimated price

$3013-0

Website

https://www.aa.com

Plane from Raleigh/Durham Airport to Knoxville Airport

Average Duration

4h 3m

Estimated price

$3016-3017

Website

https://www.united.com

Plane from Raleigh/Durham Airport to Knoxville Airport

Average Duration

4h 27m

Estimated price

$3018-3017

Durham to Knoxville: Overview of Bus, Train, Flight, and Car Trips

Traveling between Durham and Knoxville offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.

🚗 Embark on a scenic road trip from Durham to Knoxville covering a distance of 339 miles in just under 6 hours. Enjoy the changing landscapes as you traverse through the heart of the Appalachian region. 💰 Indulge in budget-friendly travel options with prices ranging between $60 to $90 for the journey by car from Durham to Knoxville. Plan your pit stops strategically to explore charming towns, local eateries, and breathtaking views along the way.

Average price

$60 - $90

🛫 Flying from Durham to Knoxville will involve a stopover as there are no direct flights between Raleigh/Durham Airport and Knoxville Airport. The quickest flight with one stop takes approximately 3 hours and 12 minutes. 🌆 Airlines such as United Airlines, Delta, and American Airlines operate flights from Raleigh/Durham Airport to Knoxville Airport, offering travelers options for their journey. The total travel time by plane from Durham to Knoxville is around 5 hours and 40 minutes. 💸 Prices for flights between Durham and Knoxville can vary, with ticket costs ranging from $140 to $823.

Departure Point

Raleigh/Durham Airport

Arrival Point

Knoxville Airport. The quickest flight takes 3h 12m and has one stopover

Frequently asked questions

Find out more about the route from Durham to Knoxville.

Or choose the category:

The distance between Durham and Knoxville is approximately 282 miles or 339.1 miles by road. The travel times vary depending on the mode of transportation. By train and bus, it takes approximately 14 hours and 20 minutes. By plane, the travel time is about 5 hours and 32 minutes. By car, it takes approximately 5 hours and 53 minutes. Lastly, by bus, the travel time is around 14 hours and 52 minutes.

The most cost-effective transportation option for traveling from Durham to Knoxville is driving. It takes approximately 5 hours and 53 minutes and can cost between $60 and $90 for fuel, depending on the type of vehicle and current gas prices. However, for those looking for a quicker option, flying is the most time-efficient choice. With a flight duration of approximately 5 hours and 32 minutes, it provides a faster way to reach Knoxville, although the cost can range between $160 and $400 depending on the airline and time of booking.

There is a range of prices for bus tickets between Knoxville and Durham, with fares ranging from $18 to $157. The cost of the ticket typically depends on factors such as the departure time and the level of comfort or amenities offered. It is advisable to compare prices from different bus operators and book in advance to secure the best deal for your journey.

To travel from Durham to Knoxville without using public transportation, you can drive the distance of approximately 339 miles. The journey usually takes around 5 hours and 53 minutes by car. The cost of the trip can range between $60 to $90 depending on factors like fuel consumption and tolls.

To travel from Durham to Knoxville without a car, the best option is to take a train and then a bus. This journey takes approximately 14 hours and 20 minutes and costs between $130 and $500. Another option is to take a plane, which is faster and takes around 5 hours and 32 minutes, but the cost may be higher. Overall, using public transportation is a convenient and affordable way to travel between these two cities without a car.

No, there is no direct bus link between Durham and Knoxville. However, there are bus services available with transfers in Washington, DC. The journey takes approximately 14 hours and 52 minutes. Buses operated by Flixbus USA depart from Durham Bus Stop and arrive at Knoxville via Massachusetts Ave Ne + First St Ne and Washington, DC. Alternatively, there are other transportation options such as trains or flights that can provide a faster and more direct route between the two cities.

The flight duration between Durham and Knoxville with one stopover, is approximately 3 hours and 4 minutes. However, there are no direct flights available. The cost of a flight between Knoxville and Durham typically ranges from $165 to $393, depending on various factors such as the airline, the time of booking, and the class of service chosen.

There are plenty of accommodation options available near Knoxville. You can choose from over 196 hotels, with prices starting as low as $44. Whether you are looking for budget-friendly options or luxury hotels, there is something for everyone in Knoxville. Some popular hotels in the area include The Tennessean Hotel, Hilton Knoxville, and Hampton Inn & Suites Knoxville. It is recommended to book in advance to secure your preferred choice of accommodation.

Durham, NC, USA to Knoxville, TN, USA from $132: 6 ways by bus, train, flight or car

How to Get from Durham to Knoxville: Cheapest, Fastest and Best Way

Compare Train, Bus, Flight, and Driving Options

See more options

Traveling From Durham to Knoxville

Best Neighbourhoods in Knoxville

Best Times To Visit Knoxville's Attractions

Knoxville Weather: What to Expect Year-Round

Dining Recommendation in Knoxville

Durham - Knoxville operators

Durham to Knoxville: Overview of Bus, Train, Flight, and Car Trips

Frequently asked questions

Trips from Durham

Trips to Knoxville

Popular routes