Florence, SC, USA to Chicago, IL, USA from $49: 9 ways by bus, train, flight or car

Compare Travel Options and Prices

How to Get from Florence to Chicago: Cheapest, Fastest and Best Way

1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.

$49 by trainBest price

1102 kmDistance

4h 14m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Florence to Chicago with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

See more options

Sort by

Browse car rentals Explore flights

Traveling From Florence to Chicago

The journey from Florence to Chicago offers a striking contrast between the charming, laid-back atmosphere of a small Southern town and the vibrant, bustling lifestyle of a major Midwestern city.

Best Neighbourhoods in Chicago

Chicago's neighborhoods each offer distinct vibes and experiences for visitors.

Lincoln Park

• Home to the Lincoln Park Zoo.

• Offers numerous parks and waterfront access.

Wicker Park

• Known for its vibrant arts scene.

• Offers eclectic shops and eateries.

Hyde Park

• Home of the University of Chicago.

• Features beautiful historical architecture.

Best Times To Visit Chicago's Attractions

Timing your visits can greatly enhance your experience of Chicago's highlights.

Millennium Park

Visit early weekday mornings for a peaceful stroll and fewer crowds.

The Art Institute of Chicago

Evenings on Thursdays and Fridays offer extended hours and quieter galleries.

Navy Pier

Go during off-peak hours, such as early afternoons on weekdays, for a more relaxed atmosphere.

Chicago Weather: What to Expect Year-Round

Chicago experiences a humid continental climate with hot summers and cold winters, making spring and fall the most pleasant times to visit. Weather conditions can significantly impact your travel plans, so being prepared for sudden changes is essential.

Dining Recommendation

Savor the iconic Chicago deep-dish pizza at Lou Malnati's, where the rich, cheesy layers and buttery crust present a bold contrast to the lighter, pasta-focused cuisine of Florence. The lively atmosphere and local ingredients create a dining experience that celebrates Chicago's hearty culinary flair.

Florence - Chicago operators

Explore transport companies operating between Florence and Chicago, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Bus Show bus routes

Contact phone

+1 404-591-2750

Website

southeasternstages.com

Bus from Florence to Columbia

Average Duration

Estimated price

$852-39720

Bus from Florence to Atlanta, GA

Average Duration

6h 10m

Estimated price

$749-2435

Website

palmlandlines.com

Bus from Atlanta, GA to Chicago, IL

Average Duration

14h 40m

Estimated price

$492-3973

Contact phone

+1 214-849-8100

Website

greyhound.com

Bus from Atlanta Bus Station to Chicago Bus Station

Average Duration

16h 10m

Estimated price

$494-745

Contact phone

+1 (855) 626-8585

Website

flixbus.com

Bus from Atlanta Bus Station to Chicago Bus Station

Average Duration

15h 45m

Estimated price

$2434-4036

Train Show train routes

Contact phone

+1 800-872-7245

Website

amtrak.com

Train from Florence Amtrak Station to Washington Union Station

Average Duration

8h 16m

Estimated price

$2433-745

Train from Rockville Amtrak to Chicago Union Station

Average Duration

17h 16m

Estimated price

$2430-746

Train from Florence Amtrak Station to Alexandria

Average Duration

7h 37m

Estimated price

$2439-39780

Train from Alexandria to Chicago Union Station

Average Duration

23h 41m

Estimated price

$3971-850

Plane Show flights

Website

southwest.com

Plane from Myrtle Beach (MYR) to Chicago Midway (MDW)

Average Duration

2h 11m

Estimated price

$4034-4035

Website

delta.com

Plane from Myrtle Beach (MYR) to Chicago Midway (MDW)

Average Duration

4h 36m

Estimated price

$492-493

Website

aa.com

Plane from Columbia (CAE) to Chicago O'Hare (ORD)

Average Duration

2h 28m

Estimated price

$498-495

Website

united.com

Plane from Columbia (CAE) to Chicago O'Hare (ORD)

Average Duration

2h 27m

Estimated price

$498-3970

Website

spirit.com

Plane from Myrtle Beach to Chicago O'Hare

Average Duration

2h 10m

Estimated price

$3971-490

Florence to Chicago: Overview of Bus, Train, Flight, and Car Trips

Traveling between Florence and Chicago offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.

🚗 Embark on a scenic road trip from Florence to Chicago spanning 881 miles of diverse landscapes and charming towns along the way. 💸 The cost of this journey ranges from $160 to $240, offering flexibility for budget-conscious travelers looking to explore the Windy City by car. 🌆 After a drive of approximately 14 hours and 46 minutes, arrive in Chicago, ready to immerse yourself in the vibrant culture, iconic architecture, and delicious cuisine of this bustling city on the shores of Lake Michigan.

Average price

$160 - $240

💰 With ticket prices ranging from $49 to $397, this 27-hour train adventure offers a budget-friendly and relaxing option for your travel from Florence to Chicago. Prepare for a memorable and laid-back experience on this cross-country train ride.

Departure Point

Florence Amtrak Station

Arrival Point

Chicago Union Station

🛫 Flying from Florence to Chicago is convenient with a direct flight from Myrtle Beach Airport to Chicago Midway Airport, taking only 2 hours and 5 minutes.

Departure Point

Myrtle Beach Airport

Arrival Point

Chicago Midway Airport

🚌 Traveling from Florence to Chicago by bus involves a journey with transfers through Atlanta. The entire trip typically takes around 23 hours and 20 minutes. 🚌 The prices for a bus ticket between Chicago and Florence can vary, ranging from $132 to $181 for the 21-hour and 35-minute journey.

Departure Point

Florence station

Arrival Point

Chicago Bus Station

Frequently asked questions

Find out more about the route from Florence to Chicago.

Or choose the category:

The distance between Florence and Chicago is approximately 685 miles by air. The quickest way to travel between the two cities is by taking a flight from Florence to Chicago Midway, which typically takes around 5 hours and 18 minutes. If you prefer to travel by train, it would take approximately 27 hours and 16 minutes. By car, the journey from Florence to Chicago would take around 14 hours and 46 minutes, while taking a bus would typically take about 21 hours and 35 minutes.

The most cost-effective option for traveling from Florence to Chicago is by taking a bus via Atlanta, which typically costs between $90 and $170 and takes approximately 21 hours and 35 minutes. However, if time efficiency is a priority, the quickest way to reach Chicago is by taking a bus to Myrtle Beach and then flying to Chicago Midway, which usually takes around 5 hours and 18 minutes and can cost between $150 and $600. It is important to consider both cost and time when deciding on the best mode of transportation for your journey.

The prices of a train ticket between Florence and Chicago can range from $49 to $397 depending on factors such as date and time of travel, class of service, and availability. On the other hand, the prices of a bus ticket between Chicago and Florence can vary from $93 to $161. It is advisable to check for the best deals and book in advance to secure lower prices for both modes of transportation.

To get from Florence to Chicago without using public transportation, you can drive. The road distance between the two cities is 881 miles, and it takes approximately 14 hours and 46 minutes to drive from Florence to Chicago. The cost of driving varies depending on factors such as gas prices and vehicle efficiency, but it usually ranges from $160 to $240.

The best way to travel from Florence to Chicago without a car is by taking a bus via Atlanta. The journey takes approximately 21 hours and 35 minutes and can cost between $90 to $170. Another option would be to take a train, which takes 27 hours and 16 minutes. Alternatively, you can take a bus to Myrtle Beach and then fly to Chicago Midway, which takes 5 hours and 18 minutes.

There is no direct train link between Florence and Chicago. However, there are train services available with transfers that take approximately 27 hours and 16 minutes. The journey involves departing from Florence Amtrak Station and arriving at Chicago Union Station via Union Station, Red Line Center Platform, and Rockville Amtrak. Similarly, there is no direct bus link between Florence and Chicago, but there are bus services with transfers that take approximately 23 hours. The journey involves departing from Florence and arriving at Chicago Train Station via Atlanta Bus Station.

The flight from Florence to Chicago typically takes around 2 hours and 5 minutes. The quickest and most convenient option is to take a direct flight from Myrtle Beach Airport to Chicago Midway Airport. As for the cost, ticket prices vary depending on the time of booking and availability, but on average, it can range from $150 to $350 for a one-way ticket. It is recommended to check with different airlines and compare prices to find the best deal.

There are numerous options for accommodation near Chicago. With over 1116 hotels available, you have a wide range of choices to suit your budget and preferences. Prices for hotels in Chicago start at $58 per night, offering affordable options for travelers. It is advisable to research and book in advance to secure the best rates and ensure availability during your stay.

Florence, SC, USA to Chicago, IL, USA from $49: 9 ways by bus, train, flight or car

How to Get from Florence to Chicago: Cheapest, Fastest and Best Way

Compare Train, Bus, Flight, and Driving Options

See more options

Traveling From Florence to Chicago

Best Neighbourhoods in Chicago

Best Times To Visit Chicago's Attractions

Chicago Weather: What to Expect Year-Round

Dining Recommendation

Florence - Chicago operators

Florence to Chicago: Overview of Bus, Train, Flight, and Car Trips

Frequently asked questions

Trips from Florence

Trips to Chicago

Popular routes