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Florence, SC, USA to Knoxville, TN, USA from $60: 4 ways by bus, train, flight or car

Compare Travel Options and Prices

from
Florence, United States of America
to
Knoxville, United States of America

How to Get from Florence to Knoxville: Cheapest, Fastest and Best Way

1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.

$60 - OtherBest price
550 kmDistance
5h 40m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Florence to Knoxville with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

Company
various
Train
Bus
Drive
Drive
Average Duration
14h  23m
Estimated price
$274-488
Recommended
Company
various
Drive
Average Duration
5h  53m
Estimated price
$60-90
Cheapest
route map
Distance: 550 km
Duration: 5h 40m

See more options

Company
various
Train
Bus
Taxi
Drive
Drive
Average Duration
16h  13m
Estimated price
$309-617
Company
American Airlines
Plane
Average Duration
5h  40m
Estimated price
$324-1030
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Traveling From Florence to Knoxville

Traveling from Florence to Knoxville offers a striking contrast between the charming, historic scenery of Florence and the vibrant, music-filled streets of Knoxville.

Best Neighbourhoods in Knoxville

Knoxville’s neighborhoods offer diverse experiences for every visitor.

Old City
• Vibrant arts scene with local galleries.
• Numerous bars and restaurants with live music.
Market Square
• Bustling hub with shops and eateries.
• Hosts regular events and farmers' markets.
South Knoxville
• Beautiful river views and outdoor parks.
• Home to attractions like Ijams Nature Center.

Best Times To Visit Knoxville's Attractions

Planning your visit to Knoxville can help you enjoy its attractions without the rush.

World's Fair Park
Weekdays in the early morning offer a peaceful stroll with fewer visitors.
Knoxville Museum of Art
Visit on Thursdays for free admission and fewer crowds.
Ijams Nature Center
Mornings during weekdays provide a quiet retreat into nature.

Knoxville Weather: What to Expect Year-Round

Knoxville experiences a humid subtropical climate with hot summers and mild winters, making spring and fall the best times to visit for pleasant temperatures. Weather impacts outdoor activities, so checking forecasts can help you plan your itinerary effectively.

Dining Recommendation in Knoxville

Be sure to try the smoked meats at Sweet P's Barbeque, where the rich, smoky flavors offer a delicious contrast to the traditional Italian fare found in Florence. The lively atmosphere combined with locally sourced ingredients creates a distinctly Southern experience that adds a new dimension to your culinary adventures.

Florence - Knoxville operators

Explore transport companies operating between Florence and Knoxville, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Train
Contact phone
+1 800-872-7245
Website
https://www.amtrak.com/home.html

Train from Florence Amtrak Station to Fayetteville Amtrak Station

Average Duration
1h 21m
Estimated price
$2746-2747

Train from Selma to Charlotte Amtrak Station

Average Duration
4h 18m
Estimated price
$2742-27430
Bus
Contact phone
+1 214-849-8100
Website
https://www.greyhound.com/

Bus from Fayetteville Bus Station to Charlotte Bus Station

Average Duration
3h 35m
Estimated price
$4882-48870
Contact phone
+1 828-327-2340
Website
http://hickoryhop.com

Bus from Charlotte Airport to Willie Brooks BBQ - Boone

Average Duration
2h 15m
Estimated price
$3098-3099

Bus from Charlotte Airport to Blowing Rock - Tanger Outlets

Average Duration
2h
Estimated price
$3098-90
Shuttle
Contact phone
+1-423-725-5988
Website
http://blackbearresorttn.com

Shuttle from Boone to Black Bear Resort

Average Duration
1h
Estimated price
$27426-0

Shuttle from Black Bear Resort to Hot Springs, NC

Average Duration
1h 15m
Estimated price
$27496-0
Taxi
Contact phone
+1 828-719-8477
Website
https://facebook.com

Taxi from Blowing Rock - Tanger Outlets to Black Bear Resort

Average Duration
1h 21m
Estimated price
$48820-30900
Plane
Website
http://aa.com

Plane from Florence (FLO) to Knoxville (TYS)

Average Duration
5h 20m
Estimated price
$2744-2745

Florence to Knoxville: Overview of Bus, Train, Flight, and Car Trips

Traveling between Florence and Knoxville offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.

🚗 Embark on a scenic road trip from Florence to Knoxville covering a distance of 342 miles through charming Southern landscapes. ⏰ Enjoy approximately 5 hours and 53 minutes of driving time, soaking in the changing scenery and small-town charm along the way. 💰 Save on travel costs with car expenses ranging from $60 to $90, making it an affordable yet memorable journey from Florence to Knoxville by road.
Average price
$60 - $90
🛫 Flying from Florence to Knoxville involves a connecting flight as there are no direct flights available. The quickest option with one stopover typically takes around 5 hours and 18 minutes. 🛬 American Airlines provides flights from Florence Airport to Knoxville Airport, offering a convenient way to reach your destination in approximately 5 hours and 40 minutes. The airline ensures a comfortable journey for travelers looking to explore Knoxville. 💸 The prices for flights between Knoxville and Florence can vary, ranging from $324 to $1030.
Departure Point
Florence Airport
Arrival Point
Knoxville Airport. The quickest flight takes 5h 18m and has one stopover

Frequently asked questions

Find out more about the route from Florence to Knoxville.

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The distance between Florence and Knoxville is approximately 266 miles by air and 341.7 miles by road. The typical travel time by plane is around 3 hours and 51 minutes, while it takes about 5 hours and 53 minutes to drive by car. If you prefer public transportation, taking a train and then a bus would take approximately 17 hours and 29 minutes, while taking a bus directly can take around 19 hours and 37 minutes.
The most cost-effective and time-efficient transportation option for traveling from Florence to Knoxville is to fly. It takes around 3 hours and 51 minutes and costs between $260 and $850. Driving is a more affordable option, costing between $60 and $90, but it takes longer, approximately 5 hours and 53 minutes. Ultimately, it depends on your budget and time constraints.
The prices of a bus ticket between Knoxville and Florence can range from $53 to $202. These prices may vary depending on factors such as the time of year, demand, and the type of bus service chosen. It is recommended to check with different bus companies or online booking platforms to find the best prices and options for your specific travel dates.
To travel from Florence to Knoxville without using public transportation, you can consider driving. The distance between the two cities is approximately 342 miles, and it takes around 5 hours and 53 minutes to drive. The cost of driving can vary from $60 to $90 depending on factors such as gas prices and vehicle efficiency.
The best way to travel from Florence to Knoxville without a car is by taking a combination of train and bus. This journey usually takes around 17 hours and 29 minutes and costs between $25 and $240. Alternatively, you can also consider taking a flight, which is faster but generally more expensive, with a typical travel time of 3 hours and 51 minutes. Overall, the train and bus option provides a more affordable and convenient way to travel between these two cities without a car.
Yes, there is a connection between Florence and Knoxville but it is not a direct one. There are bus services available that require transfers in Richmond, Massachusetts Avenue NE + First St NE, and Washington, DC. The total travel time for this route is approximately 19 hours and 37 minutes, including the transfers. The bus services are operated by Greyhound USA and OurBus.
The flight between Florence and Knoxville typically takes around 3 hours and 29 minutes with one stopover. However, there are no direct flights available between the two airports. The cost of a flight between Knoxville and Florence can range from $264 to $830, depending on factors such as the airline, season, and advance booking.
There are plenty of options for accommodation near Knoxville. With 196+ hotels available, you can find a variety of choices that suit your preferences and budget. Prices start at $44, making it possible to find affordable options as well. Whether you prefer a luxury hotel or a budget-friendly option, there is something for every traveler in Knoxville.

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