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Myrtle Beach, SC, USA to Knoxville, TN, USA from $164: 3 ways by bus, train, flight or car

Compare Travel Options and Prices

from
Myrtle Beach, United States of America
to
Knoxville, United States of America

How to Get from Myrtle Beach to Knoxville: Cheapest, Fastest and Best Way

1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.

$164 - Bus, taxi, driveBest price
528 kmDistance
3h 28m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Myrtle Beach to Knoxville with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

Company
various
Plane
Average Duration
3h  28m
Estimated price
$175-632
Recommended
Company
Greyhound USA
Bus
Taxi
Drive
Average Duration
17h  46m
Estimated price
$164-305
Cheapest
route map
Distance: 528 km
Duration: 3h 28m

See more options

Company
various
Drive
Average Duration
7h  23m
Estimated price
$70-110
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Traveling From Myrtle Beach to Knoxville

Your journey from the sandy shores of Myrtle Beach to the mountainous landscapes of Knoxville offers a striking contrast, blending beach relaxation with vibrant city life and outdoor adventures.

Best Neighbourhoods in Knoxville

Knoxville features diverse neighborhoods, each with its own charm and appeal.

Market Square
• Vibrant dining and shopping scene
• Frequent live music events
Old City
• Rich historic architecture
• Trendy bars and art galleries
South Knoxville
• Scenic parks and trails
• Close to the Tennessee River

Best Times To Visit Knoxville's Attractions

Knowing when to visit Knoxville's attractions can greatly enhance your experience.

Knoxville Zoo
Visit on weekdays during the spring or fall for smaller crowds and comfortable weather.
Ijams Nature Center
Early mornings or late afternoons on weekdays offer peaceful pathways and wildlife spotting.
World's Fair Park
Go in the early morning or on weekday evenings to enjoy serene views and quieter spaces.

Knoxville Weather: What to Expect Year-Round

Knoxville experiences a humid subtropical climate, with hot summers and mild winters, making spring and fall the ideal times to explore the city. The varied weather can affect your travel plans, so packing layers and checking forecasts will help you enjoy outdoor activities and events all year long.

Dining in Knoxville: A Unique Experience

Try the slow-smoked barbecue at Smoky Bones, a restaurant that highlights Tennessee's rich culinary tradition with bold, smoky flavors that stand in contrast to Myrtle Beach's seafood-focused cuisine. The inviting atmosphere, combined with locally sourced ingredients, brings a distinct Southern charm to your dining experience.

Myrtle Beach - Knoxville operators

Explore transport companies operating between Myrtle Beach and Knoxville, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Plane Show flights
Website
aa.com

Plane from Myrtle Beach (MYR) to Knoxville (TYS)

Average Duration
3h 45m
Estimated price
$1753-1754
Website
delta.com

Plane from Myrtle Beach (MYR) to Knoxville (TYS)

Average Duration
3h 36m
Estimated price
$1755-650
Website
united.com

Plane from Myrtle Beach (MYR) to Knoxville (TYS)

Average Duration
4h 35m
Estimated price
$1753-1756
Bus
Contact phone
+1 214-849-8100
Website
greyhound.com

Bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transit

Average Duration
1h 40m
Estimated price
$1757-1758

Bus from Wilmington Cape Fear Public Transit to Charlotte Bus Station

Average Duration
6h 15m
Estimated price
$1759-6320

Bus from Charlotte Bus Station to Asheville

Average Duration
2h 55m
Estimated price
$1752-6321
all-pages.other Show other routes
Contact phone
+1 828-333-1976
Website
avltaxi.com

Other from Elkwood Ave at Merrimon Ave to Allen Gap

Average Duration
45m
Estimated price
$17510-6322

Myrtle Beach to Knoxville: Overview of Bus, Train, Flight, and Car Trips

Traveling between Myrtle Beach and Knoxville offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.

🚗 Embark on an exciting road trip from Myrtle Beach to Knoxville! The scenic drive covers a distance of 409 miles, promising a mix of beautiful landscapes and charming pit stops along the way. ⏰ With an estimated travel time of 7 hours and 23 minutes, you can enjoy the journey at a leisurely pace, taking in the sights and sounds of the South as you make your way to Knoxville. The road trip offers a perfect opportunity to bond with travel companions or enjoy some solo reflection time. 💵 Budget-wise, expect to spend between $70 to $110 on gas and potential toll fees for the journey. Plan your trip accordingly to ensure a smooth and cost-effective travel experience from Myrtle Beach to Knoxville by car.
Average price
$70 - $110
🛫 Traveling from Myrtle Beach to Knoxville by plane involves a flight duration of around 3 hours and 4 minutes, with a single stopover along the way. 💸 The cost of a flight between Myrtle Beach and Knoxville can range anywhere from $175 to $632, depending on the airline and time of booking.
Departure Point
Myrtle Beach Airport
Arrival Point
Knoxville Airport. The quickest flight takes 3h 4m and has one stopover
Useful tips for plane travellers
• Expect layovers in hubs like Charlotte or Atlanta when flying from Myrtle Beach to Knoxville, so plan for a longer travel time and check your layover duration carefully.
• When you arrive at McGhee Tyson Airport (TYS) in Knoxville, follow the signs to baggage claim and then look for the ground transportation area to easily locate taxis and rideshare services.
• Taxi fares from McGhee Tyson Airport to downtown Knoxville typically range from $30 to $40; consider checking out the airport's ground transportation page for the latest pricing and options: Knoxville Airport Ground Transportation.

Frequently asked questions

Find out more about the route from Myrtle Beach to Knoxville.

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The distance between Myrtle Beach and Knoxville is 328 miles. By car, the typical travel time is around 7 hours and 23 minutes. Taking a bus from Myrtle Beach to Knoxville would take approximately 23 hours and 13 minutes. The fastest mode of transportation is by plane, with a travel time of 3 hours and 36 minutes.
The most cost-effective and time-efficient transportation option for traveling from Myrtle Beach to Knoxville would be to fly. It takes approximately 3 hours and 36 minutes to fly from Myrtle Beach to Knoxville. The cost of the flight ranges from $200 to $750. Driving is also an option, which takes about 7 hours and 23 minutes and costs $70 to $110. However, flying is the quickest and most convenient choice for this journey.
When traveling from Myrtle Beach to Knoxville, the prices of a bus ticket can range from $132 to $264. This price variation may depend on factors such as the time of year, availability, and type of bus service. It is recommended to check with different bus companies or online booking platforms to get the most accurate and up-to-date pricing information for your specific travel dates.
To travel from Myrtle Beach to Knoxville without using public transportation, you can opt for driving. The road distance between the two cities is approximately 409 miles, and it takes around 7 hours and 23 minutes to drive from Myrtle Beach to Knoxville. The prices for renting a car and getting from Myrtle Beach to Knoxville range from $70 to $110, depending on factors such as the type of vehicle and time of travel.
To travel from Myrtle Beach to Knoxville without a car, the best option is to take a bus and a train. The journey takes approximately 20 hours and 44 minutes and the cost can range from $45 to $290. The exact duration and price may vary depending on the specific bus and train schedules. It's recommended to check with the bus and train operators for the most up-to-date information and to book tickets in advance.
No, there is no direct link between Myrtle Beach and Knoxville. However, there are bus services available with transfers that can take you from Myrtle Beach to Knoxville. The journey typically takes around 23 hours and 13 minutes. The bus services are operated by Southeastern Stages and NYTN Bus.
The flight duration between Myrtle Beach and Knoxville can vary depending on the route and number of stopovers. The quickest option with one stopover takes approximately 3 hours and 12 minutes. However, there are no direct flights available. The cost of a flight between the two cities can range from $205 to $732, depending on factors such as the airline, time of booking, and availability. It is advisable to check with various airlines and booking websites for the most accurate and up-to-date prices.
There are plenty of accommodation options near Knoxville with over 196 hotels to choose from. Prices for hotels in the area start at $44 per night, offering a range of budgets for travelers. Whether you prefer luxury hotels or budget-friendly options, there is something for everyone in Knoxville. It is advisable to book in advance to secure the best deals and ensure availability during your stay.

Trips from Myrtle Beach

Trips to Knoxville