
Sioux Falls, SD, USA to Des Moines, IA, USA from $72: 3 ways by bus, train, flight or car
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How to Get from Sioux Falls to Des Moines: Cheapest, Fastest and Best Way
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Get detailed, step-by-step directions below for your trip from Sioux Falls to Des Moines with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

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Traveling From Sioux Falls to Des Moines
Embarking on your journey from Sioux Falls to Des Moines reveals an intriguing contrast, where the serene landscapes of South Dakota meet the vibrant urban energy of Iowa's capital.
Best Neighbourhoods in Des Moines
Des Moines boasts a variety of neighborhoods, each with its own charm.
Best Times To Visit Des Moines's Attractions
Timing your visits can enhance your experience in Des Moines's attractions.
Des Moines Weather: What to Expect Year-Round
Des Moines experiences a humid continental climate, with hot summers and cold winters that shape your travel plans throughout the year. The best times to visit are typically spring and fall, when mild temperatures enhance outdoor activities and sightseeing.
Dining Recommendation
In Des Moines, don't miss the chance to try the famous fried chicken at the East Village's unique eatery, Centro, where local ingredients elevate traditional flavors. This dining experience stands out from Sioux Falls with its vibrant atmosphere and creative twists on classic dishes, showcasing the city's culinary innovation.
Sioux Falls - Des Moines operators
Explore transport companies operating between Sioux Falls and Des Moines, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.
Plane from Sioux Falls (FSD) to Des Moines (DSM)
Plane from Sioux Falls (FSD) to Des Moines (DSM)
Plane from Sioux Falls (FSD) to Des Moines (DSM)
Plane from Sioux Falls (FSD) to Des Moines (DSM)
Bus from Sioux Falls, SD to Omaha, NE
Bus from Omaha, NE to Des Moines, IA
Bus from Omaha, NE to Des Moines, IA
Sioux Falls to Des Moines: Overview of Bus, Train, Flight, and Car Trips
Traveling between Sioux Falls and Des Moines offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.
Frequently asked questions
Find out more about the route from Sioux Falls to Des Moines.
Trips from Sioux Falls
- Sioux Falls to Okoboji
- Sioux Falls to Chamberlain
- Sioux Falls to Chicago
- Sioux Falls to Worthington
- Sioux Falls to Windom
- Sioux Falls to Vermillion
- Sioux Falls to Watertown
- Sioux Falls to Huron
- Sioux Falls to Pipestone
- Sioux Falls to Norfolk
- Sioux Falls to Pierre
- Sioux Falls to Rapid City
- Sioux Falls to Deadwood
- Sioux Falls to Sturgis
- Sioux Falls to Salt Lake City
- Sioux Falls to Rochester
- Sioux Falls to Aberdeen
- Sioux Falls to Fargo
- Sioux Falls to Indianapolis
- Sioux Falls to Nashville
- Sioux Falls to Brookings
- Sioux Falls to Duluth
- Sioux Falls to Orlando
- Sioux Falls to Las Vegas
- Sioux Falls to Gillette
- Sioux Falls to Badlands National Park
- Sioux Falls to Dell Rapids
- Sioux Falls to Marshall
- Sioux Falls to Denver
- Sioux Falls to Minneapolis
- Sioux Falls to Bismarck
- Sioux Falls to Billings
- Sioux Falls to San Diego
- Sioux Falls to Mitchell
- Sioux Falls to Sioux City
- Sioux Falls to Yankton
- Sioux Falls to Omaha
- Sioux Falls to Kansas City
- Sioux Falls to Des Moines
- Sioux Falls to Kansas City
Trips to Okoboji
- Chicago to Des Moines
- Newton to Des Moines
- Minneapolis to Des Moines
- Dubuque to Des Moines
- Pella to Des Moines
- Indianapolis to Des Moines
- Storm Lake to Des Moines
- Creston to Des Moines
- Davenport to Des Moines
- Oskaloosa to Des Moines
- Madison to Des Moines
- Peoria to Des Moines
- Milwaukee to Des Moines
- Detroit to Des Moines
- Lincoln to Des Moines
- Omaha to Des Moines
- Kearney to Des Moines
- Iowa City to Des Moines
- Boston to Des Moines
- Fargo to Des Moines
- Seattle to Des Moines
- Houston to Des Moines
- Boone to Des Moines
- Saint Louis to Des Moines
- Ames to Des Moines
- Mason City to Des Moines
- Perry to Des Moines
- Dallas to Des Moines
- Story City to Des Moines
- Moline to Des Moines
- Charles City to Des Moines
- Cedar Rapids to Des Moines
- Waterloo to Des Moines
- Greenfield to Des Moines
- Kansas City to Des Moines
- Burlington to Des Moines
- Denison to Des Moines
- Eagle Grove to Des Moines
- Lincoln to Des Moines
- Kansas City to Des Moines