1map logoGo to main page

Knoxville, TN, USA to Key West, FL, USA from $180: 4 ways by bus, train, flight or car

Compare Travel Options and Prices

from
Knoxville, United States of America
to
Key West, United States of America

How to Get from Knoxville to Key West: Cheapest, Fastest and Best Way

1Map provides directions to cities, towns, landmarks, attractions, and addresses worldwide, offering thousands of multi-modal routes to easily get you from point A to point B.

$180 by carBest price
1655 kmDistance
4h 5m Fastest

Compare Train, Bus, Flight, and Driving Options

Get detailed, step-by-step directions below for your trip from Knoxville to Key West with 1Map travel planner. Easily compare ticket prices, explore various transport options, and find the best routes for a seamless and cost-effective travel experience.

Company
Various
Plane
Average Duration
4h  5m
Estimated price
$133-520
Recommended
Company
Various
Drive
Average Duration
17h  40m
Estimated price
$180-270
Cheapest
route map
Distance: 1655 km
Duration: 4h 5m

See more options

Company
Various
Drive
Plane
Average Duration
4h  18m
Estimated price
$153-355
Company
Various
Drive
Drive
Taxi
Bus
Train
Average Duration
38h  51m
Estimated price
$383-905
Browse car rentalsExplore flights

Traveling From Knoxville to Key West

Your journey from Knoxville to Key West offers a striking contrast between the picturesque Appalachian Mountains and the vibrant, sun-soaked beaches of the Florida Keys.

Best Neighborhoods in Key West

Key West features diverse neighborhoods, each offering its own unique vibe.

Old Town
• Home to historic architecture and vibrant nightlife.
• Close to top attractions like Duval Street and Hemingway House.
New Town
• Offers modern shopping and dining experiences.
• Features accessible beaches and family-friendly parks.
Bahama Village
• Showcases rich Caribbean culture and colorful art.
• Great local restaurants serving authentic Bahamian cuisine.

Best Times To Visit Key West's Attractions

Timing your visits can greatly enhance your Key West experience.

Ernest Hemingway Home and Museum
Visiting early in the morning provides a quieter, more reflective atmosphere.
Mallory Square
Arriving at sunset allows you to witness the sunset celebration without large crowds.
Fort Zachary Taylor Historic State Park
Weekday mornings offer a peaceful beach experience and fewer visitors.

Key West Weather: What to Expect Year-Round

Key West enjoys a tropical climate, with warm temperatures year-round and occasional rain showers. The best time to visit is during the cooler months from November to April, when the weather enhances outdoor activities and beach time.

Dining Recommendation in Key West

Try the fresh caught conch fritters at Blue Heaven, a vibrant outdoor cafe that captures the laid-back island spirit. This dish, enriched with local ingredients and served amidst colorful roosters wandering freely, offers a refreshing contrast to the hearty, comfort food style you'll find in Knoxville.

Knoxville - Key West operators

Explore transport companies operating between Knoxville and Key West, with prices starting at . These companies offer competitive pricing, flexible schedules, and comfortable travel experiences.

Plane Show flights
Website
delta.com

Plane from Knoxville (TYS) to Key West (EYW)

Average Duration
4h 28m
Estimated price
$1335-1336

Plane from Asheville (AVL) to Key West (EYW)

Average Duration
4h 23m
Estimated price
$1335-1337
Website
aa.com

Plane from Knoxville (TYS) to Key West (EYW)

Average Duration
4h 42m
Estimated price
$1338-13340

Plane from Knoxville (TYS) to Key West (EYW)

Average Duration
5h 16m
Estimated price
$1338-13340

Plane from Asheville (AVL) to Key West (EYW)

Average Duration
4h 45m
Estimated price
$1338-13350
Website
allegiantair.com

Plane from Asheville (AVL) to Key West (EYW)

Average Duration
2h 2m
Estimated price
$1339-5200
Train
Contact phone
+1 800-872-7245
Website
amtrak.com

Train from Charlotte Amtrak Station to Cary

Average Duration
2h 51m
Estimated price
$5201-5202

Train from Cary to Hollywood Amtrak Station

Average Duration
20h 40m
Estimated price
$5209-1532
Bus
Contact phone
+1-423-725-5988
Website
blackbearresorttn.com

Bus from Hot Springs, NC to Black Bear Resort

Average Duration
1h 15m
Estimated price
$0-1537
Contact phone
+1 828-327-2340
Website
hickoryhop.com

Bus from Blowing Rock - Tanger Outlets to Charlotte Airport

Average Duration
2h
Estimated price
$1538-1539
Contact phone
+1 (855) 626-8585
Website
flixbus.com

Bus from Miami Airport Station to Key West

Average Duration
3h 55m
Estimated price
$3551-52010
Other Show other routes
Contact phone
+1-423-426-6003

Other from Black Bear Resort to Blowing Rock - Tanger Outlets

Average Duration
1h 20m
Estimated price
$3552-1338

Knoxville to Key West: Overview of Bus, Train, Flight, and Car Trips

Traveling between Knoxville and Key West offers a variety of convenient options to suit your preferences, schedule, and budget. Whether you prioritize affordability, speed, or comfort, you’re sure to find the perfect way to travel without compromising on quality or convenience.

Useful tips for plane travellers
• When booking, compare flights with both Delta and American Airlines; considering the layover options can significantly reduce travel time, as Delta typically routes through Atlanta while American connects through Miami.
• Upon arriving at Key West International Airport, expect a small but busy terminal; be prepared for quick baggage claim, and consider renting a bicycle from the local rental companies available at the airport to easily navigate the island.
• Taxi rides from Key West Airport to the city center usually cost around $15 to $20; you can find the taxi stand outside of the terminal, and it's recommended to confirm the fare upfront to avoid any surprises.

Frequently asked questions

Find out more about the route from Knoxville to Key West.

Or choose the category:
The distance between Knoxville and Key West is approximately 803 miles. By plane, it takes around 5 hours and 16 minutes to reach Key West from Knoxville. Taking a combination of bus and train, the journey takes about 38 hours and 36 minutes. If driving, it takes around 17 hours and 40 minutes to travel from Key West to Knoxville, while the bus takes approximately 35 hours and 34 minutes.
The most cost-effective way to travel from Knoxville to Key West is by taking a bus and train, which costs between $70 and $480 and takes approximately 38 hours and 36 minutes. However, if time is a priority, the quickest option is to drive to an airport and then take a flight, which takes around 5 hours and 13 minutes and costs between $170 and $700. It ultimately depends on your budget and time constraints when determining the best transportation option.
The prices for a bus ticket from Knoxville to Key West range from $110 to $418. These prices can vary depending on factors such as the time of year, demand, and type of service. It is recommended to check with different bus companies or online platforms for the most accurate and up-to-date pricing information.
To travel from Knoxville to Key West without using public transportation, you can opt to drive. The road distance is approximately 1029 miles, and it takes around 17 hours and 40 minutes to drive. The cost of the trip can vary, with prices ranging from $180 to $270 for gas and tolls.
To travel from Knoxville to Key West without a car, the best option is to take a bus. The journey takes approximately 35 hours and 34 minutes and fares range from $110 to $420. Another alternative is to combine bus and train travel, which takes 38 hours and 36 minutes. While there are other modes of transportation available, such as flying, taking a bus is the most convenient and cost-effective option for travelers without a car.
Yes, there is a way to travel between Knoxville and Key West but it involves transfers. There is no direct bus service, but you can take a bus from Knoxville to Washington Union Station, then transfer to another bus that will take you to Key West. The total travel time for this route is approximately 35 hours and 34 minutes. The bus services are operated by OurBus and FlixBus USA.
The flight duration from Knoxville to Key West with one stopover typically takes around 3 hours and 55 minutes. However, please note that direct flights are not available between the two cities. The cost of a flight ticket between Key West and Knoxville can vary, ranging from $388 to $1071, depending on factors like the airline, time of booking, and availability. It is always recommended to check with airlines for the most up-to-date pricing and flight options.
There are various options for accommodation near Key West. With over 466 hotels available, travelers have plenty of choices to suit their preferences and budgets. Prices for hotels in Key West start at $142, offering a range of options for different budgets. Whether you're looking for a luxury resort, a cozy bed and breakfast, or a budget-friendly option, there is something for everyone in Key West.

Trips from Knoxville

Trips to Chicago